COVID‐19 induces neuroinflammation and suppresses peroxisomes in the brain

A Roczkowsky, D Limonta, JP Fernandes… - Annals of …, 2023 - Wiley Online Library
Objective Peroxisome injury occurs in the central nervous system (CNS) during multiple
virus infections that result in neurological disabilities. We investigated host neuroimmune …

Caspase cleavage of gasdermin E causes neuronal pyroptosis in HIV-associated neurocognitive disorder

JP Fernandes, WG Branton, EA Cohen, G Koopman… - Brain, 2024 - academic.oup.com
Abstract Despite effective antiretroviral therapies, 20–30% of persons with treated HIV
infection develop a neurodegenerative syndrome termed HIV-associated neurocognitive …

Dysregulation of Gut Microbiota‐Derived Neuromodulatory Amino Acid Metabolism in Human Immunodeficiency Virus‐Associated Neurocognitive Disorder: An …

X Chen, J Wei, Z Li, Y Zhang, X Zhang… - Annals of …, 2024 - Wiley Online Library
Objective Although accumulating evidence implicating altered gut microbiota in human
immunodeficiency virus (HIV) infection and neurodegenerative disorders; however, the …

Neuro-immune deconvolution analysis of OAS3 as a transcriptomic central node in HIV-associated neurocognitive disorders

C Sanfilippo, P Castrogiovanni, M Vinciguerra… - Journal of the …, 2023 - Elsevier
Neurological complications of AIDS (NeuroAIDS) include primary HIV-associated
neurocognitive disorder (HAND). OAS3 is an enzyme belonging to the 2′, 5 …

[PDF][PDF] CLINICAL AND PATHOGENETIC FEATURES OF DAMAGE TO THE NERVOUS SYSTEM AT THE INITIAL CLINICAL STAGES OF HIV-INFECTION

ДС Сосновенко, ОМ Чемич, МД Чемич - Інфекційні хвороби, 2022 - ojs.tdmu.edu.ua
Conclusions. As a result of the war in Ukraine, the epidemiological control of infectious
diseases on the territory of the country was violated. HIV-infection and the absence or …