Vimentin diversity in health and disease

F Danielsson, MKK Peterson, H Caldeira Araújo… - Cells, 2018 - mdpi.com
Vimentin is a protein that has been linked to a large variety of pathophysiological conditions,
including cataracts, Crohn's disease, rheumatoid arthritis, HIV and cancer. Vimentin has also …

Vimentin in cancer and its potential as a molecular target for cancer therapy

A Satelli, S Li - Cellular and molecular life sciences, 2011 - Springer
Vimentin, a major constituent of the intermediate filament family of proteins, is ubiquitously
expressed in normal mesenchymal cells and is known to maintain cellular integrity and …

Triple-negative breast cancer: disease entity or title of convenience?

L Carey, E Winer, G Viale, D Cameron… - Nature reviews Clinical …, 2010 - nature.com
This Review outlines the understanding and management of triple-negative breast cancer
(TNBC). TNBC shares morphological and genetic abnormalities with basal-like breast …

Epithelial-mesenchymal transition in breast cancer relates to the basal-like phenotype

D Sarrió, SM Rodriguez-Pinilla, D Hardisson, A Cano… - Cancer research, 2008 - AACR
Epithelial-mesenchymal transition (EMT) is defined by the loss of epithelial characteristics
and the acquisition of a mesenchymal phenotype. In carcinoma cells, EMT can be …

Epithelial—mesenchymal and mesenchymal—epithelial transitions in carcinoma progression

H Hugo, ML Ackland, T Blick… - Journal of cellular …, 2007 - Wiley Online Library
Like a set of bookends, cellular, molecular, and genetic changes of the beginnings of life
mirror those of one of the most common cause of death—metastatic cancer. Epithelial to …

Development, anatomy, histology, lymphatic drainage, clinical features, and cell differentiation markers of canine mammary gland neoplasms

KU Sorenmo, R Rasotto, V Zappulli… - Veterinary …, 2011 - journals.sagepub.com
Mammary neoplasms are the most common neoplasm in female dogs. This article describes
the embryologic development, normal anatomy, and histology of the canine mammary gland …

NF‐κB and epithelial to mesenchymal transition of cancer

C Min, SF Eddy, DH Sherr… - Journal of cellular …, 2008 - Wiley Online Library
During progression of an in situ to an invasive cancer, epithelial cells lose expression of
proteins that promote cell–cell contact, and acquire mesenchymal markers, which promote …

Vimentin and epithelial-mesenchymal transition in human breast cancer–observations in vitro and in vivo

MI Kokkinos, R Wafai, MK Wong, DF Newgreen… - Cells Tissues …, 2007 - karger.com
Breast cancer is a highly prevalent disease among women worldwide. While the expression
of certain proteins within these tumours is used for prognosis and selection of therapies …

Epithelial Mesenchymal Transition Traits in Human Breast Cancer Cell Lines Parallel the CD44hi/CD24lo/- Stem Cell Phenotype in Human Breast Cancer

T Blick, H Hugo, E Widodo, M Waltham, C Pinto… - Journal of mammary …, 2010 - Springer
We review here the recently emerging relationship between epithelial-mesenchymal
transition (EMT) and breast cancer stem cells (BCSC), and provide analyses of published …

Epithelial to mesenchymal transition and breast cancer

E Tomaskovic-Crook, EW Thompson, JP Thiery - Breast cancer research, 2009 - Springer
Epithelial-mesenchymal plasticity in breast carcinoma encompasses the phenotypic
spectrum whereby epithelial carcinoma cells within a primary tumor acquire mesenchymal …