Carbonic anhydrase (CA, EC 4.2. 1.1) is a protein that is especially well-suited to serve as a
model in many types of studies in biophysics, bioanalysis, the physical-organic chemistry of …

Ion mobility measurements can be used to obtain structural information for large polyatomic
ions in the gas phase. The methods are flexible and can be applied to a wide range of …

Neutralization-reionization mass spectrometry (MS) 1 is of unique value for preparing and
characterizing highly reactive and unstable neutral species, such as the intermediate in the …

For proteins of< 20 kDa, this new radical site dissociation method cleaves different and
many more backbone bonds than the conventional MS/MS methods (eg, collisionally …

Matrix Assisted Laser Desorption/Ionization (MALDI) is a very widely used analytical
method, but has been developed in a highly empirical manner. Deeper understanding of …

Ion mobility measurements have been used to examine the geometries of naked BPTI
(bovine pancreatic trypsin inhibitor) and cytochrome c ions in the gas phase, as a function of …

The field of electrospray ionization mass spectrometry is reviewed with emphasis placed
upon advances in the elucidation of fundamental mechanistic aspects of the ionization …

Ion mobility-mass spectrometry (IM-MS) can be a powerful tool for determining structural
information about ions in the gas phase, from small covalent analytes to large, native-like or …

The dielectric constants of myoglobin, apomyoglobin, the B fragment of staphylococcal
protein A, and the immunoglobulin-binding domain of streptococcal protein G are calculated …

An ion mobility/mass spectrometry technique has been developed to record mass-resolved
ion mobility distributions for multiple ions simultaneously. The approach involves a new …