Exosomes are a type of extracellular vesicles, produced within multivesicular bodies, that
are then released into the extracellular space through a merging of the multivesicular body …

The optimal treatment for complex fractures and large bone defects is an important unsolved
issue in orthopedics and related specialties. Approximately 5–10% of fractures fail to heal …

Mesenchymal stromal cells (MSCs) are self-renewing, culture-expandable adult stem cells
that have been isolated from a variety of tissues, and possess multipotent differentiation …

The therapeutic benefits of mesenchymal stromal cell (MSC) transplantation are attributed to
their secreted factors, including extracellular vesicles (EVs) and soluble factors. The …

Objectives The present study aimed to investigate whether exosomes derived from miR‐375‐
overexpressing human adipose mesenchymal stem cells (hASCs) could enhance bone …

Mesenchymal stem cells (MSCs) are being extensively investigated for their potential in
tissue engineering and regenerative medicine. However, recent evidence suggests that the …

Mesenchymal stem cell-derived exosomes (MSC-exos), with its inherent capacity to
modulate cellular behavior, are emerging as a novel cell-free therapy for bone regeneration …

Mesenchymal stem cells (MSCs) are on the cusp of regenerative medicine due to their
differentiation capacity, favorable culture conditions, ability to be manipulated in vitro, and …

Mesenchymal stromal cells (MSCs) for basic research and clinical applications are
manufactured and developed as unique cell products by many different manufacturers and …

Mesenchymal stromal/stem cells (MSCs) are multipotent adult stem cells that support
homeostasis during tissue regeneration. In the last decade, cell therapies based on the use …