The cycle of eukaryotic transcription, from initiation to elongation and termination is
regulated at multiple steps. Coordinated action of regulatory factors keeps in check the …

In the past decade, remarkable progress has been made in reprogramming terminally
differentiated somatic cells and cancer cells into induced pluripotent cells and cancer cells …

This review analyses the literature concerning non-fluorescent and fluorescent probes for
nucleic acid imaging in fixed and living cells from the point of view of their suitability for …

Transcription factor (TF) proteins are master regulators of transcriptional activity and gene
expression. TF-based gene regulation is a promising approach for many biological …

Spinal cord regeneration is limited due to various obstacles and complex pathophysiological
events after injury. Combination therapy is one approach that recently garnered attention for …

Induced pluripotent stem (iPS) cells present a seminal discovery in cell biology and promise
to support innovative treatments of so far incurable diseases. To translate iPS technology …

Overexpression of bovine growth hormone (bGH) in transgenic (PEPCK-bGH) mice induces
resistance to insulin, which is compensated by a major increase in insulin levels. In these …

At specific DNA sites, nickel (II) salts promote the assembly of designed components,
namely a bis (histidine)‐modified peptide that is derived from a bZIP transcription factor and …

N-(4-Chloro-3-(trifluoromethyl) phenyl)-2-ethoxybenzamide (CTB) is a small molecule that
functions by altering the chromatin architecture to modulate gene expression. We report a …

DNA binding specificity of transcription factor (TF) has broad impact on cell physiology and
development and in evolution. However, DNA-binding specificity of most known TFs still …