The C Factor: Cognitive dysfunction as a transdiagnostic dimension in psychopathology

A Abramovitch, T Short, A Schweiger - Clinical Psychology Review, 2021 - Elsevier
Research into cognitive functions across psychological disorders suggests that cognitive
deficiencies may be present across multiple disorders, potentially pointing to a …

[HTML][HTML] Obsessive-compulsive disorder: puzzles and prospects

TW Robbins, MM Vaghi, P Banca - Neuron, 2019 - cell.com
Obsessive-compulsive disorder is a severe and disabling psychiatric disorder that presents
several challenges for neuroscience. Recent advances in its genetic and developmental …

[HTML][HTML] Advancing understanding of executive function impairments and psychopathology: bridging the gap between clinical and cognitive approaches

HR Snyder, A Miyake, BL Hankin - Frontiers in psychology, 2015 - frontiersin.org
Executive function (EF) is essential for successfully navigating nearly all of our daily
activities. Of critical importance for clinical psychological science, EF impairments are …

A fronto–striato–subthalamic–pallidal network for goal-directed and habitual inhibition

M Jahanshahi, I Obeso, JC Rothwell… - Nature Reviews …, 2015 - nature.com
Classically, the basal ganglia have been considered to have a role in producing habitual
and goal-directed behaviours. In this article, we review recent evidence that expands this …

Obsessive–compulsive disorder: an integrative genetic and neurobiological perspective

DL Pauls, A Abramovitch, SL Rauch… - Nature Reviews …, 2014 - nature.com
Obsessive–compulsive disorder (OCD) is characterized by repetitive thoughts and
behaviours that are experienced as unwanted. Family and twin studies have demonstrated …

The general factor of psychopathology

GT Smith, EA Atkinson, HA Davis… - Annual review of …, 2020 - annualreviews.org
An important advance in understanding and defining mental disorders has been the
development of empirical approaches to mapping dimensions of dysfunction and their …

Biological markers for anxiety disorders, OCD and PTSD: A consensus statement. Part II: Neurochemistry, neurophysiology and neurocognition

B Bandelow, D Baldwin, M Abelli… - The World Journal of …, 2017 - Taylor & Francis
Objective: Biomarkers are defined as anatomical, biochemical or physiological traits that are
specific to certain disorders or syndromes. The objective of this paper is to summarise the …

Obsessive-compulsive disorder is associated with broad impairments in executive function: A meta-analysis

HR Snyder, RH Kaiser, SL Warren… - Clinical Psychological …, 2015 - journals.sagepub.com
Obsessive-compulsive disorder (OCD) is a serious and often chronically disabling condition.
The current dominant model of OCD focuses on abnormalities in prefrontal-striatal circuits …

[HTML][HTML] Specific frontostriatal circuits for impaired cognitive flexibility and goal-directed planning in obsessive-compulsive disorder: evidence from resting-state …

MM Vaghi, PE Vértes, MG Kitzbichler… - Biological …, 2017 - Elsevier
Background A recent hypothesis has suggested that core deficits in goal-directed behavior
in obsessive-compulsive disorder (OCD) are caused by impaired frontostriatal function. We …

Cognitive inflexibility in obsessive-compulsive disorder

P Gruner, C Pittenger - Neuroscience, 2017 - Elsevier
Abstract Obsessive-Compulsive Disorder (OCD) is characterized by maladaptive patterns of
repetitive, inflexible cognition and behavior that suggest a lack of cognitive flexibility …