Advances in powder bed fusion 3D printing in drug delivery and healthcare

A Awad, F Fina, A Goyanes, S Gaisford… - Advanced Drug Delivery …, 2021 - Elsevier
Powder bed fusion (PBF) is a 3D printing method that selectively consolidates powders into
3D objects using a power source. PBF has various derivatives; selective laser …

Spatially offset Raman spectroscopy

S Mosca, C Conti, N Stone, P Matousek - Nature Reviews Methods …, 2021 - nature.com
Spatially offset Raman spectroscopy (SORS) is a spectroscopic technique that allows for the
non-invasive chemical characterization of diffusely scattering materials, ranging from …

A review of disintegration mechanisms and measurement techniques

D Markl, JA Zeitler - Pharmaceutical research, 2017 - Springer
Pharmaceutical solid dosage forms (tablets or capsules) are the predominant form to
administer active pharmaceutical ingredients (APIs) to the patient. Tablets are typically …

Pharmaceutical solvates, hydrates and amorphous forms: A special emphasis on cocrystals

AM Healy, ZA Worku, D Kumar, AM Madi - Advanced drug delivery reviews, 2017 - Elsevier
Active pharmaceutical ingredients (APIs) may exist in various solid forms, which can lead to
differences in the intermolecular interactions, affecting the internal energy and enthalpy, and …

Mesoporous silica particles as drug delivery systems—the state of the art in loading methods and the recent progress in analytical techniques for monitoring these …

K Trzeciak, A Chotera-Ouda, II Bak-Sypien… - Pharmaceutics, 2021 - mdpi.com
Conventional administration of drugs is limited by poor water solubility, low permeability,
and mediocre targeting. Safe and effective delivery of drugs and therapeutic agents remains …

Deep learning for Raman spectroscopy: a review

R Luo, J Popp, T Bocklitz - Analytica, 2022 - mdpi.com
Raman spectroscopy (RS) is a spectroscopic method which indirectly measures the
vibrational states within samples. This information on vibrational states can be utilized as …

Biomolecular and bioanalytical applications of infrared spectroscopy–A review

KB Beć, J Grabska, CW Huck - Analytica chimica acta, 2020 - Elsevier
Infrared (IR; or mid-infrared, MIR; 4000-400 cm− 1; 2500–25,000 nm) spectroscopy has
become one of the most powerful and versatile tools at the disposal of modern bioscience …

Pharmaceutical cocrystals: New solid phase modification approaches for the formulation of APIs

A Karagianni, M Malamatari, K Kachrimanis - Pharmaceutics, 2018 - mdpi.com
Cocrystals can be used as an alternative approach based on crystal engineering to enhance
specific physicochemical and biopharmaceutical properties of active pharmaceutical …

[HTML][HTML] Application of quality by design in the current drug development

L Zhang, S Mao - Asian journal of pharmaceutical sciences, 2017 - Elsevier
Quality by Test was the only way to guarantee quality of drug products before FDA launched
current Good Manufacturing Practice. To clearly understand the manufacture processes …

Materials and technologies to combat counterfeiting of pharmaceuticals: current and future problem tackling

H Zhang, D Hua, C Huang, SK Samal… - Advanced …, 2020 - Wiley Online Library
The globalization of drug trade leads to the expansion of pharmaceutical counterfeiting. The
immense threat of low quality drugs to millions of patients is considered to be an under …