Mitochondria are specialized compartments that produce requisite ATP to fuel cellular
functions and serve as centers of metabolite processing, cellular signaling, and apoptosis …

As with all organisms that must organize and condense their DNA to fit within the limited
volume of a cell or a nucleus, mammalian mitochondrial DNA (mtDNA) is packaged into …

Mitochondrial transcription factor A (TFAM) employs DNA bending to package mitochondrial
DNA (mtDNA) into nucleoids and recruit mitochondrial RNA polymerase (POLRMT) at …

The mitochondrial genome, mtDNA, is present in multiple copies in cells and encodes
essential subunits of oxidative phosphorylation complexes. mtDNA levels have to change in …

Mitochondrial transcription factor A (TFAM) plays a critical role in mitochondrial transcription
initiation and mitochondrial DNA (mtDNA) packaging. Both functions require DNA binding …

Atomic force microscopy (AFM) has made significant contributions to the study of protein-
DNA interactions by making it possible to topographically image biological samples. A …

Mitochondrial DNA (mtDNA) is packaged by association with specific proteins in compact
DNA-protein complexes named mitochondrial nucleoids (mt-nucleoids). The budding yeast …

HMGB3 protein belongs to the group of HMGB proteins from the superfamily of nuclear
proteins with high electrophoretic mobility. HMGB proteins play an active part in almost all …

Mitochondrial DNA (mtDNA) molecules are packaged into compact nucleo-protein structures
called mitochondrial nucleoids (mt-nucleoids). Their compaction is mediated in part by high …

Among the class of enediyne antibiotics endowed with potent antitumour activities, the
calicheamicin derivative known as ozogamicin is selectively targeted to several leukaemia …