Sex-specific effects of neuropathic pain on long-term pain behavior and mortality in mice
M Millecamps, SG Sotocinal, JS Austin, LS Stone… - Pain, 2023 - journals.lww.com
Human epidemiological studies suggest that chronic pain can increase mortality risk. We
investigated whether this was true in mice so that underlying mechanisms might be …
investigated whether this was true in mice so that underlying mechanisms might be …
Structural changes of the multifidus in animal models of intervertebral disk degeneration: a systematic review
Y Wang, X Zhao, X Zhang, Y Yang, W Zhang… - Frontiers in …, 2024 - frontiersin.org
Study design Low back pain (LBP) is a widespread clinical symptom affecting nearly all age
groups and is a leading cause of disability worldwide. Degenerative changes in the spine …
groups and is a leading cause of disability worldwide. Degenerative changes in the spine …
The progression of neurovascular features and chemokine signatures of the intervertebral disc with degeneration
R Walk, K Broz, L Jing, R Potter, CE Gonzalez… - …, 2024 - pmc.ncbi.nlm.nih.gov
Inflammatory cytokine production and de novo neurovascularization have been identified in
painful, degenerated intervertebral discs (IVDs). However, the temporal trajectories of these …
painful, degenerated intervertebral discs (IVDs). However, the temporal trajectories of these …
[HTML][HTML] Characterization of pain-related behaviors in a rat model of acute-to-chronic low back pain: single vs. multi-level disc injury
MF Barbe, FL Chen, RH Loomis, MY Harris… - Frontiers in Pain …, 2024 - ncbi.nlm.nih.gov
Methods Twenty-three Sprague-Dawley adult female rats were used: 8 received disc
puncture (DP) of one lumbar IVD (L5/6, DP-1); 8 received DP of two lumbar IVDs (L4/5 & …
puncture (DP) of one lumbar IVD (L5/6, DP-1); 8 received DP of two lumbar IVDs (L4/5 & …
A mouse coccygeal intervertebral disc degeneration model with tail‐looping constructed using a suturing method
W Xie, Z Huang, Z Huang, D Luo… - Animal Models and …, 2024 - Wiley Online Library
Backgroud Intervertebral disc degeneration (IDD) is one of the common degenerative
diseases. Due to ethical constraints, it is difficult to obtain sufficient research on humans, so …
diseases. Due to ethical constraints, it is difficult to obtain sufficient research on humans, so …
Bone-IVD Crosstalk and the Role of RAGE Signaling in an IVD Injury Model
RE Walk - 2024 - search.proquest.com
Low back pain (LBP) is the number one musculoskeletal cause of disability with a lifetime
prevalence of up to 85%. The causes of LBP are multifactorial with potential contributions …
prevalence of up to 85%. The causes of LBP are multifactorial with potential contributions …
Сучасні підходи до моделювання in vivo дегенеративних захворювань хребта
V Radchenko, M Skidanov, N Ashukina… - ORTHOPAEDICS …, 2022 - otp-journal.com.ua
Поширеність захворюваності й інвалідності через поперековий біль у світі постійно
зростають. Для зменшення соціально-економічних наслідків дегенеративних …
зростають. Для зменшення соціально-економічних наслідків дегенеративних …