Wound healing, fibroblast heterogeneity, and fibrosis

HE Talbott, S Mascharak, M Griffin, DC Wan… - Cell stem cell, 2022 - cell.com
Fibroblasts are highly dynamic cells that play a central role in tissue repair and fibrosis.
However, the mechanisms by which they contribute to both physiologic and pathologic …

The dynamics of the skin's immune system

AV Nguyen, AM Soulika - International journal of molecular sciences, 2019 - mdpi.com
The skin is a complex organ that has devised numerous strategies, such as physical,
chemical, and microbiological barriers, to protect the host from external insults. In addition …

Wireless, closed-loop, smart bandage with integrated sensors and stimulators for advanced wound care and accelerated healing

Y Jiang, AA Trotsyuk, S Niu, D Henn, K Chen… - Nature …, 2023 - nature.com
Abstract 'Smart'bandages based on multimodal wearable devices could enable real-time
physiological monitoring and active intervention to promote healing of chronic wounds …

Single-cell transcriptomes of the human skin reveal age-related loss of fibroblast priming

L Solé-Boldo, G Raddatz, S Schütz, JP Mallm… - Communications …, 2020 - nature.com
Fibroblasts are an essential cell population for human skin architecture and function. While
fibroblast heterogeneity is well established, this phenomenon has not been analyzed …

Experimental models and methods for cutaneous wound healing assessment

DS Masson‐Meyers, TAM Andrade… - International journal …, 2020 - Wiley Online Library
Wound healing studies are intricate, mainly because of the multifaceted nature of the wound
environment and the complexity of the healing process, which integrates a variety of cells …

Wound healing dynamics, morbidity, and complications of palatal soft‐tissue harvesting

L Tavelli, S Barootchi, M Stefanini… - Periodontology …, 2023 - Wiley Online Library
Palatal‐tissue harvesting is a routinely performed procedure in periodontal and peri‐implant
plastic surgery. Over the years, several surgical approaches have been attempted with the …

Advances in cutaneous squamous cell carcinoma

MCG Winge, LN Kellman, K Guo, JY Tang… - Nature Reviews …, 2023 - nature.com
Human malignancies arise predominantly in tissues of epithelial origin, where the stepwise
transformation from healthy epithelium to premalignant dysplasia to invasive neoplasia …

Antimicrobial peptides and their therapeutic potential for bacterial skin infections and wounds

A Pfalzgraff, K Brandenburg, G Weindl - Frontiers in pharmacology, 2018 - frontiersin.org
Alarming data about increasing resistance to conventional antibiotics are reported, while at
the same time the development of new antibiotics is stagnating. Skin and soft tissue …

Skin wound healing in humans and mice: Challenges in translational research

HD Zomer, AG Trentin - Journal of dermatological science, 2018 - Elsevier
Despite the great progress in translational research concerning skin wound healing in the
last few decades, no animal model fully predicts all clinical outcomes. The mouse is the most …

[HTML][HTML] Research techniques made simple: animal models of wound healing

A Grada, J Mervis, V Falanga - Journal of Investigative Dermatology, 2018 - Elsevier
Animal models have been developed to study the complex cellular and biochemical
processes of wound repair and to evaluate the efficacy and safety of potential therapeutic …