Magnetic resonance imaging (MRI) is recognized as the most powerful clinical imaging
modality due to its ability to generate detailed three-dimensional anatomical images with …

Chemical exchange saturation transfer (CEST) MRI has generated great interest for
molecular imaging applications because it can image low‐concentration solute molecules in …

Purpose To obtain high‐sensitivity CEST maps by exploiting the spatiotemporal correlation
between CEST images. Methods A postprocessing method accomplished by multilinear …

Purpose To develop a method that can separate and quantify the fast (> 1 kHz) and slow
exchange transfer and magnetization transfer components in Z‐spectra. Methods Z‐spectra …

Acid–base homeostasis and pH regulation are critical for normal tissue metabolism and
physiology, and brain tissue pH alters in many diseased states. Several noninvasive tissue …

Recently, radiotherapy (RT) has entered a new realm of precision cancer therapy with the
introduction of magnetic resonance (MR) imaging guided radiotherapy systems into the …

Chemical exchange saturation transfer (CEST), arterial spin labeling (ASL), and
magnetization transfer contrast (MTC) methods generate different contrasts for MRI …

We propose a method to dynamically monitor the progress of an enzymatic reaction using
NMR of hyperpolarized 129Xe in a host–guest system. It is based on a displacement assay …

Purpose Saturation transfer MRI has previously been used to probe molecular binding
interactions with signal enhancement via the water signal. Here, we detail the relayed …

Purpose There are 118 known elements. Nearly all of them have NMR active isotopes and
at least 39 different nuclei have biological relevance. Despite this, most of today's MRI is …