[HTML][HTML] The Role of Antioxidants in the Therapy of Cardiovascular Diseases—A Literature Review

E Młynarska, J Hajdys, W Czarnik, P Fularski, K Leszto… - Nutrients, 2024 - mdpi.com
Antioxidants are endogenous and exogenous substances with the ability to inhibit oxidation
processes by interacting with reactive oxygen species (ROS). ROS, in turn, are small, highly …

Impact of sodium–glucose cotransporter 2 (SGLT2) inhibitors on arterial stiffness and vascular aging—what do we know so far?(a narrative review)

CA Adam, R Anghel, DTM Marcu, O Mitu, M Roca… - Life, 2022 - mdpi.com
Vascular aging, early vascular aging or supernormal vascular aging are concepts used for
estimating the cardiovascular risk at a certain age. From the famous line of Thomas …

StackedEnC-AOP: prediction of antioxidant proteins using transform evolutionary and sequential features based multi-scale vector with stacked ensemble learning

G Rukh, S Akbar, G Rehman, FK Alarfaj, Q Zou - BMC bioinformatics, 2024 - Springer
Background Antioxidant proteins are involved in several biological processes and can
protect DNA and cells from the damage of free radicals. These proteins regulate the body's …

Carbon dots as light-responsive oxidase-like nanozyme for colorimetric detection of total antioxidant capacity in fruits

J Li, Y Zhou, Y Xiao, S Cai, C Huang, S Guo, Y Sun… - Food Chemistry, 2023 - Elsevier
Abstract Evaluation of total antioxidant capacity (TAC) in fruits is essential for dietary
guidance and health monitoring. Here, we have exploited light-response carbon dots (CDs) …

Effects of Fisetin, a Plant-Derived Flavonoid, on Response to Oxidative Stress, Aging, and Age-Related Diseases in Caenorhabditis elegans

S Park, BK Kim, SK Park - Pharmaceuticals, 2022 - mdpi.com
Fisetin (3, 3′, 4′, 7-tetrahydroxyflavone), a flavonoid abundant in various fruits and
vegetables, including apple, strawberry, and onion, shows several beneficial effects such as …

Gpx3 and Egr1 are involved in regulating the differentiation fate of cardiac fibroblasts under pressure overload

G Li, Y Qin, Z Cheng, X Cheng, R Wang… - Oxidative Medicine …, 2022 - Wiley Online Library
Objectives. Although myocardial fibrosis is a common pathophysiological process
associated with many heart diseases, the molecular mechanisms regulating the …

SGLT2 inhibitors in aging-related cardiovascular disease: A review of potential mechanisms

Y Zhang, Y He, S Liu, L Deng, Y Zuo, K Huang… - American Journal of …, 2023 - Springer
Population aging combined with higher susceptibility to cardiovascular diseases in older
adults is increasing the incidence of conditions such as atherosclerosis, myocardial …

Role of angiotensin II in aging

W Yi, F Chen, H Zhang, P Tang, M Yuan… - Frontiers in Aging …, 2022 - frontiersin.org
Aging is an inevitable progressive decline in physiological organ function that increases the
chance of disease and death. The renin–angiotensin system (RAS) is involved in the …

[HTML][HTML] The impact of aging on cardiac repair and regeneration

I Anwar, X Wang, RE Pratt, VJ Dzau… - Journal of Biological …, 2024 - Elsevier
In contrast to neonates and lower organisms, the adult mammalian heart lacks any capacity
to regenerate following injury. The vast majority of our understanding of cardiac …

Rejuvenation: turning back time by enhancing CISD2

CH Yeh, ZQ Shen, CC Lin, CK Lu, TF Tsai - International Journal of …, 2022 - mdpi.com
The aging human population with age-associated diseases has become a problem
worldwide. By 2050, the global population of those who are aged 65 years and older will …