In various areas of the bio-medical, pharmacological and psychological research a multitude
of behavioural tests have been used to investigate the effects of environmental, genetic and …

Background: Obsessive-compulsive disorder (OCD) is associated with affective and
cognitive symptoms causing personal distress and reduced global functioning. These have …

Accumulating evidence demonstrates that the gut microbiota affects brain function and
behavior, including depressive behavior. Antidepressants are the main drugs used for …

Background Accumulating evidence suggests that commensal bacteria consumption has the
potential to have a positive impact on stress‐related psychiatric disorders. However, the …

Objective: Major depressive disorder has been linked with inflammatory processes, but it is
unclear whether individual differences in levels of inflammatory biomarkers could help …

The synthesis and structure− activity relationship of a novel series of compounds with
combined effects on 5-HT3A and 5-HT1A receptors and on the serotonin (5-HT) transporter …

The monoamine hypothesis has been the prevailing hypothesis of depression over the last
several decades. It states that depression is associated with reduced monoamine function …

It is known that newer antidepressants, such as the selective serotonin reuptake inhibitors
(SSRIs), provide advantages in tolerability over antidepressants such as the tricyclics …

Major depression is a debilitating and recurrent disorder with a substantial lifetime risk and a
high social cost. Depressed patients generally display co-morbid symptoms, and depression …

Objective The purpose of this study was to identify genetic variants underlying the
considerable individual differences in response to antidepressant treatment. The authors …