The SOFA score—development, utility and challenges of accurate assessment in clinical trials
S Lambden, PF Laterre, MM Levy, B Francois - Critical Care, 2019 - Springer
Abstract The Sequential Organ Failure Assessment or SOFA score was developed to assess
the acute morbidity of critical illness at a population level and has been widely validated as a …
the acute morbidity of critical illness at a population level and has been widely validated as a …
Clinical review: scoring systems in the critically ill
JL Vincent, R Moreno - Critical care, 2010 - Springer
General illness severity scores are widely used in the ICU to predict outcome, characterize
disease severity and degree of organ dysfunction, and assess resource use. In this article …
disease severity and degree of organ dysfunction, and assess resource use. In this article …
Effect of therapeutic drug monitoring-based dose optimization of piperacillin/tazobactam on sepsis-related organ dysfunction in patients with sepsis: a randomized …
Purpose Insufficient antimicrobial exposure is associated with worse outcomes in sepsis. We
evaluated whether therapeutic drug monitoring (TDM)-guided antibiotic therapy improves …
evaluated whether therapeutic drug monitoring (TDM)-guided antibiotic therapy improves …
Management of acute ischemic stroke in patients with COVID-19 infection: report of an international panel
AI Qureshi, F Abd-Allah, F Al-Senani… - … Journal of Stroke, 2020 - journals.sagepub.com
Background and purpose On 11 March 2020, World Health Organization (WHO) declared
the COVID-19 infection a pandemic. The risk of ischemic stroke may be higher in patients …
the COVID-19 infection a pandemic. The risk of ischemic stroke may be higher in patients …
Effect of conservative vs conventional oxygen therapy on mortality among patients in an intensive care unit: the oxygen-ICU randomized clinical trial
Importance Despite suggestions of potential harm from unnecessary oxygen therapy,
critically ill patients spend substantial periods in a hyperoxemic state. A strategy of controlled …
critically ill patients spend substantial periods in a hyperoxemic state. A strategy of controlled …
Clinical characteristics and outcomes of critically ill patients with novel coronavirus infectious disease (COVID-19) in China: a retrospective multicenter study
J Xie, W Wu, S Li, Y Hu, M Hu, J Li, Y Yang… - Intensive care …, 2020 - Springer
Purpose An ongoing outbreak of coronavirus disease 2019 (COVID-19) emerged in Wuhan
since December 2019 and spread globally. However, information about critically ill patients …
since December 2019 and spread globally. However, information about critically ill patients …
[HTML][HTML] Albumin replacement in patients with severe sepsis or septic shock
P Caironi, G Tognoni, S Masson… - … England Journal of …, 2014 - Mass Medical Soc
Background Although previous studies have suggested the potential advantages of albumin
administration in patients with severe sepsis, its efficacy has not been fully established …
administration in patients with severe sepsis, its efficacy has not been fully established …
Mortality predictive value of APACHE II and SOFA scores in COVID‐19 patients in the intensive care unit
MT Beigmohammadi, L Amoozadeh… - Canadian …, 2022 - Wiley Online Library
Background. COVID‐19 pandemic has become a global dilemma since December 2019.
Are the standard scores, such as acute physiology and chronic health evaluation (APACHE …
Are the standard scores, such as acute physiology and chronic health evaluation (APACHE …
Phase I safety trial of intravenous ascorbic acid in patients with severe sepsis
AA Fowler, AA Syed, S Knowlson, R Sculthorpe… - Journal of translational …, 2014 - Springer
Background Parenterally administered ascorbic acid modulates sepsis-induced
inflammation and coagulation in experimental animal models. The objective of this …
inflammation and coagulation in experimental animal models. The objective of this …
Serial evaluation of the SOFA score to predict outcome in critically ill patients
FL Ferreira, DP Bota, A Bross, C Mélot, JL Vincent - Jama, 2001 - jamanetwork.com
ContextEvaluation of trends in organ dysfunction in critically ill patients may help predict
outcome. ObjectiveTo determine the usefulness of repeated measurement the Sequential …
outcome. ObjectiveTo determine the usefulness of repeated measurement the Sequential …