Transposable elements, often considered to be not important for survival, significantly
contribute to the evolution of transcriptomes, promoters, and proteomes. Reverse …

This review summarizes the knowledge about retrogenes in the context of cancer and
evolution. The retroposition, in which the processed mRNA from parental genes undergoes …

Mobile elements (MEs) collectively contribute to at least 50% of the human genome. Due to
their past incremental accumulation and ongoing DNA transposition, MEs serve as a …

Gene retrocopies arise from the reverse transcription and insertion into the genome of
processed mRNA transcripts. Although many retrocopies have acquired mutations that …

For a long time, retrocopies were considered 'junk DNA', but numerous studies have shown
that retrocopies may gain functionality and become so-called retrogenes. Retrogenes may …

Although the contribution of retrogenes to the evolution of genes and genomes has long
been recognized, the evolutionary patterns of very recently derived retrocopies that are still …

Retrotransposition is one of the main factors responsible for gene duplication and thus
genome evolution. However, the sequences that undergo this process are not only an …

Transcriptomic diversity across human populations reflects differential regulatory
mechanisms. Allelic-imbalanced gene expression is a genetic regulatory mechanism that …

Retroduplication variation (RDV), a type of retrocopy polymorphism, is considered to have
essential biological significance, but its effect on gene function and species phenotype is still …

Retroposition is an RNA-mediated mechanism to generate gene duplication, and is believed
to play an important role in genome evolution and phenotypic adaptation in various species …