Background In the 5 years that have passed since the publication of the 2018 International
Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (ICAR‐Allergic Rhinitis …

Thymic stromal lymphopoietin (TSLP) is a pleiotropic cytokine that acts on multiple cell
lineages, including dendritic cells, T cells, B cells, neutrophils, mast cells, eosinophils and …

Allergic diseases affect millions of people worldwide. An increase in their prevalence has
been associated with alterations in the gut microbiome, ie, the microorganisms and their …

The incidence of allergic diseases is increasing, and research on their epidemiology,
pathophysiology, and the prevention of onset is urgently needed. The onset of allergic …

Progress in understanding of the mechanisms underlying chronic inflammatory skin
disorders, such as atopic dermatitis and psoriasis vulgaris, has led to new treatment options …

Eosinophils are bone marrow‐derived granulocytes and are found in low numbers in the
peripheral blood of healthy subjects. In type 2 inflammatory diseases, eosinopoiesis in the …

Eosinophils are typically considered tissue-damaging effector cells in type 2 immune-related
diseases. However, they are also increasingly recognized as important modulators of …

Asthma, rhinitis, and atopic dermatitis (AD) are interrelated clinical phenotypes that partly
overlap in the human interactome. The concept of “one‐airway‐one‐disease,” coined over …

Mast cells (MCs) are best-known as key effector cells of immediate-type allergic reactions
that may even culminate in life-threatening anaphylactic shock syndromes. However …

In light of an escalating prevalence of allergic disorders, it is crucial to fully comprehend their
pathophysiology and etiology. Such knowledge would play a pivotal role in the search for …