[HTML][HTML] Resting-state connectivity in neurodegenerative disorders: Is there potential for an imaging biomarker?

C Hohenfeld, CJ Werner, K Reetz - NeuroImage: Clinical, 2018 - Elsevier
Biomarkers in whichever modality are tremendously important in diagnosing of disease,
tracking disease progression and clinical trials. This applies in particular for disorders with a …

Neuronal autophagy and mitophagy in Parkinson's disease

BN Lizama, CT Chu - Molecular aspects of medicine, 2021 - Elsevier
Autophagy is the process by which cells can selectively or non-selectively remove damaged
proteins and organelles. As the cell's main means of sequestering damaged mitochondria …

Targeting mitophagy in neurodegenerative diseases

O Antico, PW Thompson, NT Hertz… - Nature Reviews Drug …, 2025 - nature.com
Mitochondrial dysfunction is a hallmark of idiopathic neurodegenerative diseases, including
Parkinson disease, amyotrophic lateral sclerosis, Alzheimer disease and Huntington …

Severe hyposmia and aberrant functional connectivity in cognitively normal Parkinson's disease

N Yoneyama, H Watanabe, K Kawabata, E Bagarinao… - PLoS …, 2018 - journals.plos.org
Objective Severe hyposmia is a risk factor of dementia in Parkinson's disease (PD), while
the underlying functional connectivity (FC) and brain volume alterations in PD patients with …

Measuring compensation in neurodegeneration using MRI

S Gregory, JD Long, SJ Tabrizi… - Current Opinion in …, 2017 - journals.lww.com
Measuring compensation in neurodegeneration using MRI : Current Opinion in Neurology
Measuring compensation in neurodegeneration using MRI : Current Opinion in Neurology Log …

Structural white matter alterations as compensatory mechanisms in Parkinson's disease: A systematic review of diffusion tensor imaging studies

H Sanjari Moghaddam, M Dolatshahi… - Journal of …, 2020 - Wiley Online Library
Compensation is described as normal or near to normal performance in Parkinson's disease
(PD), despite the ongoing neural loss. Functional compensation typically proceeds in an …

Imaging Markers in Genetic Forms of Parkinson's Disease

A Droby, A Thaler, A Mirelman - Brain Sciences, 2023 - mdpi.com
Parkinson's disease (PD) is a complex neurodegenerative disorder characterized by motor
symptoms such as bradykinesia, rigidity, and resting tremor. While the majority of PD cases …

The role of genetic testing in the clinical practice and research of early-onset parkinsonian disorders in a hungarian cohort: Increasing challenge in genetic …

A Illés, D Csabán, Z Grosz, P Balicza, A Gézsi… - Frontiers in …, 2019 - frontiersin.org
The genetic analysis of early-onset Parkinsonian disorder (EOPD) is part of the clinical
diagnostics. Several genes have been implicated in the genetic background of …

Structural and functional MRI in familial Parkinson's disease

A Thaler - International Review of Neurobiology, 2018 - Elsevier
Between 10 and 15% of Parkinson disease (PD) cases can be traced to a genetically
identified causative mutation which currently number over 40. This enables the study of both …

[PDF][PDF] A genetikai architektúra szerepének vizsgálata Parkinsonizmusban

A Illés - 2020 - repo.lib.semmelweis.hu
A Parkinson-kór (PD) a második leggyakoribb progresszív neurodegeneratív betegség. A
legfrissebb tanulmányok szerint körülbelül 6 millió ember érintett világszerte. A 60 éves kor …