Emergence of Marburg virus: a global perspective on fatal outbreaks and clinical challenges
The Marburg virus (MV), identified in 1967, has caused deadly outbreaks worldwide, the
mortality rate of Marburg virus disease (MVD) varies depending on the outbreak and virus …
mortality rate of Marburg virus disease (MVD) varies depending on the outbreak and virus …
Filoviruses: scientific gaps and prototype pathogen recommendation
LC Dupuy, CF Spiropoulou, JS Towner… - The Journal of …, 2023 - academic.oup.com
Viruses in the family Filoviridae, including the commonly known Ebola (EBOV) and Marburg
(MARV) viruses, can cause severe hemorrhagic fever in humans and nonhuman primates …
(MARV) viruses, can cause severe hemorrhagic fever in humans and nonhuman primates …
Species-specific immunogenicity and protective efficacy of a vesicular stomatitis virus-based Sudan virus vaccine: a challenge study in macaques
A Marzi, P Fletcher, F Feldmann, G Saturday… - The Lancet …, 2023 - thelancet.com
Summary Background The recent Sudan virus (SUDV) outbreak in Uganda highlights the
need for rapid response capabilities, including development of vaccines against emerging …
need for rapid response capabilities, including development of vaccines against emerging …
A single-shot ChAd3-MARV vaccine confers rapid and durable protection against Marburg virus in nonhuman primates
R Hunegnaw, AN Honko, L Wang, D Carr… - Science translational …, 2022 - science.org
Marburg virus (MARV) causes a severe hemorrhagic fever disease in primates with mortality
rates in humans of up to 90%. MARV has been identified as a category A bioterrorism agent …
rates in humans of up to 90%. MARV has been identified as a category A bioterrorism agent …
Rapid protection of nonhuman primates against Marburg virus disease using a single low-dose VSV-based vaccine
Background Marburg virus (MARV) is the causative agent of Marburg virus disease (MVD)
which has a case fatality rate up to∼ 90% in humans. Recently, there were cases reported …
which has a case fatality rate up to∼ 90% in humans. Recently, there were cases reported …
Marburg virus disease amid COVID-19 in West Africa: an emerging and re-emerging zoonotic epidemic threat, future implications and way forward
Amid the coronavirus 2019 (COVID-19) pandemic, several African countries including
Ghana and Equatorial Guinea have reported several zoonotic outbreaks. The COVID-19 …
Ghana and Equatorial Guinea have reported several zoonotic outbreaks. The COVID-19 …
A highly attenuated panfilovirus VesiculoVax vaccine rapidly protects nonhuman primates against Marburg virus and 3 species of Ebola virus
C Woolsey, V Borisevich, KN Agans… - The Journal of …, 2023 - academic.oup.com
Abstract Background The family Filoviridae consists of several virus members known to
cause significant mortality and disease in humans. Among these, Ebola virus (EBOV) …
cause significant mortality and disease in humans. Among these, Ebola virus (EBOV) …
Marburg virus disease: global threat or isolated events?
A Marzi, H Feldmann - The Journal of Infectious Diseases, 2023 - academic.oup.com
The genus Marburgvirus, family Filoviridae, includes the single species Marburg
marburgvirus with 2 distinct viruses, Marburg virus and Ravn virus. Both viruses are …
marburgvirus with 2 distinct viruses, Marburg virus and Ravn virus. Both viruses are …
Preexisting immunity does not prevent efficacy of vesicular stomatitis virus–based filovirus vaccines in nonhuman primates
A Marzi, F Feldmann, KL O'Donnell… - The Journal of …, 2023 - academic.oup.com
Ebola virus (EBOV) and Marburg virus (MARV) made headlines in the past decade, causing
outbreaks of human disease in previously nonendemic yet overlapping areas. While EBOV …
outbreaks of human disease in previously nonendemic yet overlapping areas. While EBOV …
[PDF][PDF] Estimated future mortality from pathogens of epidemic and pandemic potential
Epidemics and pandemics pose a sporadic and sometimes severe threat to human health.
How should policymakers prioritize preventing and preparing for such events, relative to …
How should policymakers prioritize preventing and preparing for such events, relative to …