Inflammasomes and Leishmania: in good times or bad, in sickness or in health

DS Zamboni, DL Sacks - Current opinion in microbiology, 2019 - Elsevier
Highlights•Leishmania infection triggers activation of NLRP3 inflammasome in
macrophages.•Inflammasome activation in macrophages restricts intracellular parasite …

[HTML][HTML] Unravelling the unsolved paradoxes of cytokine families in host resistance and susceptibility to Leishmania infection

BO Osero, RT Aruleba, F Brombacher, R Hurdayal - Cytokine: X, 2020 - Elsevier
Leishmaniasis is a neglected disease caused by protozoan parasites of the genus
Leishmania. Successful clearance of Leishmania relies on a robust human immune …

IFN-γ-mediated control of SARS-CoV-2 infection through nitric oxide

BJA Silva, PA Krogstad, RMB Teles… - Frontiers in …, 2023 - frontiersin.org
Introduction The COVID-19 pandemic has highlighted the need to identify mechanisms of
antiviral host defense against SARS-CoV-2. One such mediator is interferon-g (IFN-γ) …

Effects of Vitamin A and K3 on Immune Function and Intestinal Antioxidant Capacity of Aged Laying Hens

L Li, Z Liu, B Fang, J Xu, X Dong, L Yang… - Brazilian Journal of …, 2022 - SciELO Brasil
This study was conducted to investigate effects of vitamin A (VA) and vitamin K3 (VK3) on
immune function and intestinal antioxidant capacity of aged laying hens. In a 3× 3 factorial …

Salvianolic acid A exhibits anti-inflammatory and antiarthritic effects via inhibiting NF-κB and p38/MAPK pathways

S Feng, H Cong, L Ji - Drug Design, Development and Therapy, 2020 - Taylor & Francis
Introduction Osteoarthritis (OA), a chronic joint disease, combines with massive inflammation
and plays a vital role in cartilage degeneration. The main strategy in clinic is controlling …

[HTML][HTML] Low-molecular-weight heparin reduces the formation of lower limb deep venous thrombosis in patients with hypertensive intracerebral hemorrhage

H Song, H Men, C Song, H Feng, H Tan… - American Journal of …, 2021 - ncbi.nlm.nih.gov
Objective: To demonstrate that low-molecular-weight heparin (LMWH) can reduce the
formation of lower limb deep venous thrombosis (DVT) and improve the quality of life (QOL) …

Prevalence Study of Trichomonas gallinae in Domestic Pigeons in Northeastern Beijing and Experimental Model of Trichomoniasis in White King Squabs Measuring …

A Ni, Y Li, AM Isa, P Wang, L Shi, J Fan, P Ge, L Jiang… - Animals, 2024 - mdpi.com
Trichomonas gallinae (T. gallinae) is a flagellated protozoan and the causative agent of
trichomoniasis, or canker, in birds. In the current study, the prevalence of T. gallinae was …

The different faces of the NLRP3 inflammasome in cutaneous Leishmaniasis: A review

A Kihel, I Hammi, D Darif, M Lemrani, M Riyad… - Cytokine, 2021 - Elsevier
Cutaneous leishmaniasis (CL) is a vector-borne parasitic disease caused by Protozoa of the
genus Leishmania. Clinical manifestations of this disease are the result of a complex …

丰富环境通过抑制NOD 样受体蛋白3 炎性小体活化缓解脂多糖小鼠的认知障碍

牛磊, 罗诗诗, 李威, 罗丹, 刘志文, 曹文宇, 徐杨… - 解剖学报, 2020 - jpxb.bjmu.edu.cn
目的探讨丰富环境(EE) 对脂多糖(LPS) 诱导的小鼠认知功能障碍的影响及其可能机制. 方法36
只3 周龄昆明小鼠进行8 周的EE 刺激或者标准环境(SE) 饲养后分为以下3 组: 标准环境+ …

Immunomodulation of Macrophages May Benefit Cutaneous Leishmaniasis Outcome

LB de Souza Lima, RA Menolli, TS Ayala - Current Tropical Medicine …, 2023 - Springer
Abstract Purpose of Review This review emerges from the necessity to gather information of
quality on the possibility to directly modulate macrophages and its functions to improve …