Design of antimicrobial peptides: progress made with human cathelicidin LL-37

G Wang, JL Narayana, B Mishra, Y Zhang… - … Peptides: Basics for …, 2019 - Springer
The incorporation of the innate immune system into humans is essential for survival and
health due to the rapid replication of invading microbes and the delayed action of the …

Antimicrobial peptides for the prevention and treatment of dental caries: A concise review

JY Niu, IX Yin, WKK Wu, QL Li, ML Mei, CH Chu - Archives of Oral Biology, 2021 - Elsevier
The objective of this study was to perform a comprehensive review of the use of
antimicrobial peptides for the prevention and treatment of dental caries. The study included …

Bioactive materials for caries management: A literature review

OL Zhang, JY Niu, IX Yin, OY Yu, ML Mei, CH Chu - Dentistry Journal, 2023 - mdpi.com
Researchers have developed novel bioactive materials for caries management. Many
clinicians also favour these materials, which fit their contemporary practice philosophy of …

The vicK gene of Streptococcus mutans mediates its cariogenicity via exopolysaccharides metabolism

Y Deng, Y Yang, B Zhang, H Chen, Y Lu… - International Journal of …, 2021 - nature.com
Streptococcus mutans (S. mutans) is generally regarded as a major contributor to dental
caries because of its ability to synthesize extracellular polysaccharides (EPS) that aid in the …

[HTML][HTML] Origami of KR-12 designed antimicrobial peptides and their potential applications

J Lakshmaiah Narayana, AF Mechesso, IIG Rather… - Antibiotics, 2024 - mdpi.com
This review describes the discovery, structure, activity, engineered constructs, and
applications of KR-12, the smallest antibacterial peptide of human cathelicidin LL-37, the …

Candida–Bacterial Biofilms and Host–Microbe Interactions in Oral Diseases

TC Negrini, H Koo, RA Arthur - Oral Mucosal Immunity and Microbiome, 2019 - Springer
Oral cavity harbors a complex and highly diverse microbial community. Cross-kingdom
interactions between Candida and oral bacteria are critical for their co-existence, which may …

Preventing biofilm formation by dairy-associated bacteria using peptide-coated surfaces

A Friedlander, S Nir, M Reches… - Frontiers in microbiology, 2019 - frontiersin.org
Biofilm-forming bacteria, which colonize the surfaces of equipment in the dairy industry, may
adversely affect the safety and quality of the milk and its products. Despite numerous efforts …

Peptide designs for use in caries management: a systematic review

OL Zhang, JY Niu, OY Yu, ML Mei… - International Journal of …, 2023 - mdpi.com
The objective of this study was to review the design methods that have been used to create
peptides for use in caries management. Two independent researchers systematically …

[HTML][HTML] Cashew nut shell liquids: Antimicrobial compounds in prevention and control of the oral biofilms

N de Oliveira Souza, DA Cunha… - Archives of oral …, 2022 - Elsevier
Objective The aim was to evaluate the antibacterial and antibiofilm activity of natural (n-
CNSL) and technical (t-CNSL) cashew nut shell liquid against streptococci and enterococci …

Cytocompatibility and synergy of EGCG and cationic peptides against bacteria related to endodontic infections, in planktonic and biofilm conditions

KS Caiaffa, VR Dos Santos, GF Abuna… - Probiotics and …, 2021 - Springer
This study evaluated the cytocompatibility and antimicrobial/antibiofilm effects of
epigallocatechin-3-gallate (EGCG) associated with peptide LL-37 and its analogue KR-12 …