Pathogenesis, diagnosis and clinical management of diabetic sensorimotor peripheral neuropathy

G Sloan, D Selvarajah, S Tesfaye - Nature Reviews Endocrinology, 2021 - nature.com
Diabetic sensorimotor peripheral neuropathy (DSPN) is a serious complication of diabetes
mellitus and is associated with increased mortality, lower-limb amputations and distressing …

Epidemiology of peripheral neuropathy and lower extremity disease in diabetes

CW Hicks, E Selvin - Current diabetes reports, 2019 - Springer
Abstract Purpose of Review Diabetic peripheral neuropathy eventually affects nearly 50% of
adults with diabetes during their lifetime and is associated with substantial morbidity …

Diabetic peripheral neuropathy: advances in diagnosis and strategies for screening and early intervention

D Selvarajah, D Kar, K Khunti, MJ Davies… - The lancet Diabetes & …, 2019 - thelancet.com
Diabetic peripheral neuropathy (DPN) is a common complication of both type 1 and 2
diabetes. It is a leading cause of lower-limb amputation and disabling neuropathic pain …

Gastroparesis

M Camilleri, V Chedid, AC Ford, K Haruma… - Nature reviews Disease …, 2018 - nature.com
Gastroparesis is a disorder characterized by delayed gastric emptying of solid food in the
absence of a mechanical obstruction of the stomach, resulting in the cardinal symptoms of …

Neurological consequences of obesity

PD O'Brien, LM Hinder, BC Callaghan… - The Lancet …, 2017 - thelancet.com
The high prevalence of obesity is associated with an enormous medical, social, and
economic burden. The metabolic dysfunction, dyslipidaemia, and inflammation caused by …

Evaluating all potential oral complications of diabetes mellitus

MJL Verhulst, BG Loos, VEA Gerdes… - Frontiers in …, 2019 - frontiersin.org
Diabetes mellitus (DM) is associated with several microvascular and macrovascular
complications, such as retinopathy, nephropathy, neuropathy, and cardiovascular diseases …

New insights into the mechanisms of diabetic complications: role of lipids and lipid metabolism

S Eid, KM Sas, SF Abcouwer, EL Feldman, TW Gardner… - Diabetologia, 2019 - Springer
Diabetes adversely affects multiple organs, including the kidney, eye and nerve, leading to
diabetic kidney disease, diabetic retinopathy and diabetic neuropathy, respectively. In both …

Type 1 diabetes

MA Atkinson, GS Eisenbarth, AW Michels - The lancet, 2014 - thelancet.com
Over the past decade, knowledge of the pathogenesis and natural history of type 1 diabetes
has grown substantially, particularly with regard to disease prediction and heterogeneity …

Peripheral neuropathy in prediabetes and the metabolic syndrome

AM Stino, AG Smith - Journal of diabetes investigation, 2017 - Wiley Online Library
Peripheral neuropathy is a major cause of disability worldwide. Diabetes is the most
common cause of neuropathy, accounting for 50% of cases. Over half of people with …

Diabetic neuropathy: clinical manifestations and current treatments

BC Callaghan, HT Cheng, CL Stables… - The lancet …, 2012 - thelancet.com
Diabetic peripheral neuropathy is a prevalent, disabling disorder. The most common
manifestation is distal symmetrical polyneuropathy (DSP), but many patterns of nerve injury …