Advances in Fourier transform infrared (FTIR) spectroscopy of biological tissues

ACS Talari, MAG Martinez, Z Movasaghi… - Applied Spectroscopy …, 2017 - Taylor & Francis
This article reviews some of the recent advances on FTIR spectroscopy in areas related to
natural tissues and cell biology. It is an update on our previously published review on the …

FTIR spectroscopy in biomedical research: How to get the most out of its potential

S Magalhães, BJ Goodfellow… - Applied Spectroscopy …, 2021 - Taylor & Francis
Abstract Fourier Transform Infrared (FTIR) Spectroscopy, in particular ATR-FTIR, is a widely
used technique that allows, in a very short time, to screen biological samples and to identify …

Standardization of complex biologically derived spectrochemical datasets

CLM Morais, M Paraskevaidi, L Cui, NJ Fullwood… - Nature protocols, 2019 - nature.com
Spectroscopic techniques such as Fourier-transform infrared (FTIR) spectroscopy are used
to study interactions of light with biological materials. This interaction forms the basis of …

Fourier-transform infrared spectroscopy coupled with a classification machine for the analysis of blood plasma or serum: a novel diagnostic approach for ovarian …

K Gajjar, J Trevisan, G Owens, PJ Keating, NJ Wood… - Analyst, 2013 - pubs.rsc.org
Currently available screening tests do not deliver the required sensitivity and specificity for
accurate diagnosis of ovarian or endometrial cancer. Infrared (IR) spectroscopy of blood …

The detection and discrimination of human body fluids using ATR FT-IR spectroscopy

CM Orphanou - Forensic science international, 2015 - Elsevier
Blood, saliva, semen and vaginal secretions are the main human body fluids encountered at
crime scenes. Currently presumptive tests are routinely utilised to indicate the presence of …

Brain tumour differentiation: rapid stratified serum diagnostics via attenuated total reflection Fourier-transform infrared spectroscopy

JR Hands, G Clemens, R Stables, K Ashton… - Journal of neuro …, 2016 - Springer
The ability to diagnose cancer rapidly with high sensitivity and specificity is essential to
exploit advances in new treatments to lead significant reductions in mortality and morbidity …

Potential of mid-infrared spectroscopy as a non-invasive diagnostic test in urine for endometrial or ovarian cancer

M Paraskevaidi, CLM Morais, KMG Lima, KM Ashton… - Analyst, 2018 - pubs.rsc.org
The current lack of an accurate, cost-effective and non-invasive test that would allow for
screening and diagnosis of gynaecological carcinomas, such as endometrial and ovarian …

Vibrational biospectroscopy coupled with multivariate analysis extracts potentially diagnostic features in blood plasma/serum of ovarian cancer patients

GL Owens, K Gajjar, J Trevisan… - Journal of …, 2014 - Wiley Online Library
Despite numerous advances in “omics” research, early detection of ovarian cancer still
remains a challenge. The aim of this study was to determine whether attenuated total …

ATR-FTIR spectroscopy coupled with chemometric analysis discriminates normal, borderline and malignant ovarian tissue: classifying subtypes of human cancer

G Theophilou, KMG Lima, PL Martin-Hirsch… - Analyst, 2016 - pubs.rsc.org
Surgical management of ovarian tumours largely depends on their histo-pathological
diagnosis. Currently, screening for ovarian malignancy with tumour markers in conjunction …

Label-free biomedical imaging with mid-IR spectroscopy

MJ Walsh, RK Reddy… - IEEE Journal of selected …, 2012 - ieeexplore.ieee.org
IR absorption imaging, especially using Fourier transform IR (FT-IR) imaging spectrometers,
is an emerging modality for biomedical applications. As opposed to current techniques that …