[HTML][HTML] Impact of oxidative stress on male and female germ cells: implications for fertility

RJ Aitken - Reproduction, 2020 - rep.bioscientifica.com
Male and female germ lines are vulnerable to oxidative stress. In spermatozoa, such stress
triggers a lipid peroxidation cascade that culminates in the generation of electrophilic lipid …

Inhibition of keratinocyte ferroptosis suppresses psoriatic inflammation

Y Shou, L Yang, Y Yang, J Xu - Cell death & disease, 2021 - nature.com
Psoriasis is a common, chronic, and recurrent inflammatory disease. It is characterized by
hyperproliferation and abnormal differentiation of keratinocytes. Keratinocyte death is also …

[HTML][HTML] Glutamine prevents upregulation of NF-kB signaling and caspase 3 activation in ischaemia/reperfusion-induced testicular damage: An animal model

OA Afolabi, DC Anyogu, MA Hamed, AF Odetayo… - Biomedicine & …, 2022 - Elsevier
Aim Testicular ischaemia/reperfusion (I/R) injury is a major consequence of testicular torsion
with possible attendant risk of male infertility. Glutamine, on the other hand, is a known …

[PDF][PDF] Role of antioxidants in preventing testicular ischemia‑reperfusion injury: a narrative review.

ZM Li - European Review for Medical & Pharmacological …, 2022 - europeanreview.org
Testicular ischemia-reperfusion injury (TIR) is a urological emergency common among male
newborns, children, and adolescents. Testicular injury and its consequences, such as …

Proanthocyanidin alleviates testicular torsion/detorsion-induced ischemia/reperfusion injury in rats

F Kazak, G Akcakavak, I Alakus, H Alakus, O Kirgiz… - Tissue and Cell, 2024 - Elsevier
Testicular torsion is an urological emergency and can lead to ischemia damage and
testicular loss if not diagnosed in time. Proanthocyanidin is reported to have anti …

Protective effect of dipeptidyl peptidase-4 inhibitors in testicular torsion/detorsion in rats: a possible role of HIF-1α and nitric oxide

WY Abdelzaher, RR Rofaeil, DME Ali… - … Archives of Pharmacology, 2020 - Springer
Spermatic cord torsion is a serious and common urologic emergency. It requires early
diagnosis for prevention of subfertility and testicular necrosis. Vildagliptin and sitagliptin are …

Sinapic acid reduces ischemia/reperfusion injury due to testicular torsion/detorsion in rats

V Unsal, E Kolukcu, F Gevrek, F Firat - Andrologia, 2021 - Wiley Online Library
This study aimed to investigate the protective effect of sinapic acid (SA) on biochemical and
histopathological changes in an experimental testicular torsion‐detorsion rat model. Twenty …

Gallic acid attenuates torsion/detorsion-induced testicular injury in rats through suppressing of HMGB1/NF-κB axis and endoplasmic reticulum stress

S Demir, İ Kazaz, G Kerimoglu, N Alemdar… - Revista internacional …, 2024 - avesis.ktu.edu.tr
It was aimed to evaluate whether gallic acid (GA) have a beneficial effect in the testicular
ischemia/reperfusion injury (IRI) model in rats for the first time. Testicular malondialdehyde …

Involvement of hypoxia-inducible factor 1-α in experimental testicular ischemia and reperfusion: effects of polydeoxyribonucleotide and selenium

P Antonuccio, G Pallio, HR Marini, N Irrera… - International Journal of …, 2022 - mdpi.com
Polydeoxyribonucleotide (PDRN) is an agonist of the A2A adenosine receptor derived from
salmon trout sperm. Selenium (Se) is a trace element normally present in the diet. We aimed …

Syringic acid ameliorates ischemia/reperfusion-induced testicular injury in rats via suppressing of HMGB1/NF-κB axis and endoplasmic reticulum stress

EA Demir, S Demir, IO Kazaz, H Kucuk… - European Journal of …, 2023 - Springer
Purpose To investigate the possible protective role of syringic acid on torsion/detorsion-
induced testicular injury using biochemical and histopathological approaches for the first …