Orofacial pain management: an overview of the potential benefits of palmitoylethanolamide and other natural agents

S Santonocito, M Donzella, P Venezia, G Nicolosi… - Pharmaceutics, 2023 - mdpi.com
Pain is the most common symptom that dentists are confronted with, whether acute (pulpitis,
acute periodontitis, post-surgery, etc.) or chronic diseases, such as periodontitis, muscle …

Piezo1 and its Inhibitors: Overview and Perspectives

ND Thien, N Hai-Nam, DT Anh, D Baecker - European Journal of Medicinal …, 2024 - Elsevier
The cation channel Piezo1, a crucial mechanotransducer found in various organs and
tissues, has gained considerable attention as a therapeutic target in recent years. Following …

Chemotherapy‐induced phlebitis via the GBP5/NLRP3 inflammasome axis and the therapeutic effect of aescin

P Liu, L Ye, Y Ren, G Zhao, Y Zhang… - British Journal of …, 2023 - Wiley Online Library
Background and Purpose Intravenous infusion of chemotherapy drugs can cause severe
chemotherapy‐induced phlebitis (CIP) in patients. However, the underlying mechanism of …

Esculin ameliorates obesity-induced insulin resistance by improving adipose tissue remodeling and activating the IRS1/PI3K/AKT/GLUT4 pathway

YY Yang, JJ Qi, SY Jiang, L Ye - Journal of Ethnopharmacology, 2024 - Elsevier
Ethnopharmacological relevance Cortex fraxini (also known as qinpi)—the bark of Fraxinus
rhynchophylla Hance (Oleaceae)—is widely used as a Chinese traditional medicinal for its …

Aescin protects against experimental benign prostatic hyperplasia and preserves prostate histomorphology in rats via suppression of inflammatory cytokines and COX …

M Raafat, AA Kamel, AH Shehata, ASF Ahmed… - Pharmaceuticals, 2022 - mdpi.com
Background: Benign prostatic hyperplasia (BPH) is the most common urogenital condition in
aging males, while inflammation and tissue proliferation constitute the main …

Effect of extrusion processing conditions on the techno-functional, antioxidant, textural properties and storage stability of wholegrain-based breakfast cereal …

FM Allai, Z Azad, BN Dar, K Gul - Italian Journal of Food Science, 2022 - itjfs.com
The central composite rotatable design was used to plan the experiments using feed
moisture (FM) content, barrel temperature (BT), screw speed (SS), and concentration of …

[HTML][HTML] Assessment of antimicrobial activity of ethanolic and aqueous extracts of Aesculus hippocastanum L.(Horse Chestnut) bark against bacteria isolated from …

YK Khar'kov, MMJ Arsene, MV Aliya… - Frontiers in Bioscience …, 2022 - imrpress.com
The search for new antimicrobials is essential to address the worldwide issue of antibiotic
resistance. The present work aimed at assessing the antimicrobial activity of Aesculus …

Development of protein rich pregelatinized whole grain cereal bar enriched with nontraditional ingredient: nutritional, phytochemical, textural, and sensory …

FM Allai, BN Dar, K Gul, M Adnan, SA Ashraf… - Frontiers in …, 2022 - frontiersin.org
This study was aimed to use extrusion cooking as a pretreatment for non-conventional
seeds (Indian horse chestnut flour) to blend them with whole grain flours (whole wheat flour …

Biopolymer chitosan surface engineering with magnesium oxide-pluronic-f127-escin nanoparticles on human breast carcinoma cell line and microbial strains

S Mickymaray, MS Al Aboody, MM Eraqi, WA Alhoqail… - Nanomaterials, 2023 - mdpi.com
Nanotechnology has been recognized as a highly interdisciplinary field of the twenty-first
century, with diverse applications in biotechnology, healthcare, and material science. One of …

Enhanced mitochondrial co-localization of β-escin micelle and pancreatic tumor accumulation relation

B Uner, AD Ergin - Journal of Drug Delivery Science and Technology, 2023 - Elsevier
Abstract β-escin, a triterpenoid saponin derived from plants, is a valuable natural product
that possesses strong anti-inflammatory, as well as the potential for anticancer effects …