The ability of the brain to store and process information relies on changing the strength of
connections between neurons. Synaptic facilitation is a form of short-term plasticity that …

Voltage-gated calcium channels are the primary mediators of depolarization-induced
calcium entry into neurons. There is great diversity of calcium channel subtypes due to …

Voltage‐gated calcium channels are essential players in many physiological processes in
excitable cells. There are three main subdivisions of calcium channel, defined by the pore …

Calmodulin (CaM) is a ubiquitous, highly conserved, eukaryotic protein that binds to and
regulates a number of diverse target proteins involved in different functions such as …

Calmodulin regulation (calmodulation) of the family of voltage-gated CaV1-2 channels
comprises a prominent prototype for ion channel regulation, remarkable for its powerful …

Voltage-gated Ca 2+ channels in presynaptic nerve terminals initiate neurotransmitter
release in response to depolarization by action potentials from the nerve axon. The strength …

Nanosecond Pulsed Electric Field (nsPEF) is an electrostimulation technique first developed
in 1995; nsPEF requires the delivery of a series of pulses of high electric fields in the order of …

Calmodulin regulation of CaV channels is a prominent Ca2+ feedback mechanism
orchestrating vital adjustments of Ca2+ entry. The long-held structural correlation of this …

BACKGROUND: Voltage-gated (Cav) Ca2+ channels are multi-subunit complexes that play
diverse roles in a wide variety of tissues. A fundamental mechanism controlling Cav channel …

Transient receptor potential (TRP) vanilloid 1 (TRPV1) is a molecular pain receptor
belonging to the TRP superfamily of nonselective cation channels. As a polymodal receptor …