Urbanization gradient, diet, and gut microbiota in Sub-Saharan Africa: a systematic review

LS Paulo, G Msema Bwire… - Frontiers in …, 2023 - frontiersin.org
Introduction As Sub-Saharan Africa (SSA) undergoes rapid urbanization changes in diet and
lifestyle have contributed to a rise in non-communicable diseases (NCDs) across the region …

Comprehensive Analysis of Gut Microbiota Composition and Functional Metabolism in Children with Autism Spectrum Disorder and Neurotypical Children …

A De Sales-Millán, P Reyes-Ferreira… - International Journal of …, 2024 - mdpi.com
This study aimed to investigate the gut microbiota composition in children with autism
spectrum disorder (ASD) compared to neurotypical (NT) children, with a focus on identifying …

Reducing the amount of Clostridium difficile in the gut microbiome reduces the behavioral projection of cognitive activity in rats

G Tevzadze, N Kiknadze… - World Academy of …, 2023 - spandidos-publications.com
It is already known that the gut microbiome bacteria colony of Clostridium difficile produces
10‑1,000‑fold more para‑cresol (p‑cresol) than other known p‑cresol‑producing bacteria in …

Effects of a gut microbiome toxin, p-cresol, on the indices of social behavior in rats

G Tevzadze, N Oniani, E Zhuravliova, N Darchia… - Neurophysiology, 2018 - Springer
At present, several studies have highlighted the relation between changes in the gut
microbiota/microbiome and a few pathologies of the CNS, including autism and other …

Effects of a gut microbiome toxin, p-Cresol, on the susceptibility to seizures in rats

G Tevzadze, Z Nanobashvili, E Zhuravliova… - Neurophysiology, 2018 - Springer
Several studies have highlighted a high comorbidity between epilepsy and autism. We
hypothesized that some similar etiological factors might affect both disorders; among such …

Gut health of children with autism spectrum disorder

E Kakabadze, K Makalatia… - World Academy of …, 2022 - spandidos-publications.com
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder, frequently
manifested by gastrointestinal symptoms. The investigation of alterations in the gut …

Reanalysis of metabolomics data reveals that microbiota transfer therapy modulates important fecal and plasma metabolite profiles in children with autism spectrum …

K Nirmalkar, F Qureshi, DW Kang, J Hahn, JB Adams… - bioRxiv, 2024 - biorxiv.org
While Autism Spectrum Disorder (ASD) is diagnosed through behavioral symptoms and
psychometric evaluations, it has also been associated with distinct metabolomic patterns. A …

Effects of a Gut Microbiome Toxin, p-Cresol, on the Contents of the NMDA2B Receptor Subunit in the Nucl. Accumbens of Rats

G Tevzadze, E Zhuravliova, M Meparishvili… - Neurophysiology, 2019 - Springer
The effects of p-cresol on the levels of subunit 2RB of NMDA receptors and also of AMPA
and GABAA receptors in the nucl. accumbens (NAc) of rats were studied. As was found, the …

Bettering of Learning Activity through Elevated P-Cresol Levels in the Brain: Insights from Active Avoidance Testing in Wistar Rats

G Tevzadze, H Zhuravliova, Z Kikvidze, N Kiknadze… - bioRxiv, 2024 - biorxiv.org
It is established that p-cresol, a compound produced by bacterial colonies within the
gastrointestinal tract of mammals, plays a contributory role in the manifestation of various …

[PDF][PDF] Besides the development of mental disorders, gut microbiome bacteria appear to play a major role in turning on cognitive activity: Outcomes of experiments …

G Tevzadze, L Shanshiashvili, D Mikeladze - 2024 - researchgate.net
The article discusses the findings of laboratory experiments conducted over the past seven
years, focusing on the investigation of the brain-gut axis. These experiments examine not …