Molecular pumps and motors

Y Feng, M Ovalle, JSW Seale, CK Lee… - Journal of the …, 2021 - ACS Publications
Pumps and motors are essential components of the world as we know it. From the complex
proteins that sustain our cells, to the mechanical marvels that power industries, much we …

Mechanisms of energy transduction by charge translocating membrane proteins

F Calisto, FM Sousa, FV Sena, PN Refojo… - Chemical …, 2021 - ACS Publications
Life relies on the constant exchange of different forms of energy, ie, on energy transduction.
Therefore, organisms have evolved in a way to be able to harvest the energy made …

[HTML][HTML] ATP synthases from archaea: the beauty of a molecular motor

G Grüber, MSS Manimekalai, F Mayer… - Biochimica et Biophysica …, 2014 - Elsevier
Archaea live under different environmental conditions, such as high salinity, extreme pHs
and cold or hot temperatures. How energy is conserved under such harsh environmental …

[引用][C] The Vital Question: Energy, Evolution, and the Origins of Complex Life

N Lane - 2015 - books.google.com
“One of the deepest, most illuminating books about the history of life to have been published
in recent years.”—The Economist The Earth teems with life: in its oceans, forests, skies and …

Cryo-EM structures of the autoinhibited E. coli ATP synthase in three rotational states

M Sobti, C Smits, ASW Wong, R Ishmukhametov… - Elife, 2016 - elifesciences.org
A molecular model that provides a framework for interpreting the wealth of functional
information obtained on the E. coli F-ATP synthase has been generated using cryo-electron …

Native mass spectrometry—A valuable tool in structural biology

M Barth, C Schmidt - Journal of Mass Spectrometry, 2020 - Wiley Online Library
Proteins and the complexes they form with their ligands are the players of cellular action.
Their function is directly linked with their structure making the structural analysis of protein …

Cross-linking mass spectrometry uncovers protein interactions and functional assemblies in synaptic vesicle membranes

S Wittig, M Ganzella, M Barth, S Kostmann… - Nature …, 2021 - nature.com
Synaptic vesicles are storage organelles for neurotransmitters. They pass through a
trafficking cycle and fuse with the pre-synaptic membrane when an action potential arrives at …

Ion mobility–mass spectrometry of a rotary ATPase reveals ATP-induced reduction in conformational flexibility

M Zhou, A Politis, RB Davies, I Liko, KJ Wu… - Nature …, 2014 - nature.com
Rotary ATPases play fundamental roles in energy conversion as their catalytic rotation is
associated with interdomain fluctuations and heterogeneity of conformational states. Using …

[HTML][HTML] Rotary ATPases—dynamic molecular machines

AG Stewart, EM Laming, M Sobti, D Stock - Current opinion in structural …, 2014 - Elsevier
Highlights•Visualization of rotary ATPases on nanometre scale by cryo-electron
microscopy.•In situ visualization of mitochondrial ATP synthase by electron cryo …

Transforming yeast into a facultative photoheterotroph via expression of vacuolar rhodopsin

A Peterson, C Baskett, WC Ratcliff, A Burnetti - Current Biology, 2024 - cell.com
Phototrophic metabolism, the capture of light for energy, was a pivotal biological innovation
that greatly increased the total energy available to the biosphere. Chlorophyll-based …