Biochemical systems theory (BST) is the foundation for a set of analytical andmodeling tools
that facilitate the analysis of dynamic biological systems. This paper depicts major …

When I am called upon to teach fluid mechanics, I always show students a copy of Newton's
Principia. I do this for a number of reasons, not least of which is the connection I hope they …

Posttranslational modification of proteins is important for signal transduction, and hence
significant effort has gone toward understanding how posttranslational modification …

For mass action kinetics, the capacity for multiple equilibria in an isothermal homogeneous
continuous flow stirred tank reactor is determined by the structure of the underlying network …

Mathematical modelling has become an established tool for studying the dynamics of
biological systems. Current applications range from building models that reproduce …

We consider the dynamics of chemical reaction networks under the assumption of mass-
action kinetics. We show that there exist reaction networks R for which the reaction rate …

We give necessary and sufficient conditions in terms of sign vectors for the injectivity of
families of polynomial maps with arbitrary real exponents defined on the positive orthant …

Chemical reaction systems are dynamical systems that arise in chemical engineering and
systems biology. In this work, we consider the question of whether the minimal (in a precise …

We consider a dynamical system, described by a system of ordinary differential equations,
and the associated interaction graphs, which are defined using the matrix of signs of the …

Mathematical models are increasingly being used to understand complex biochemical
systems, to analyse experimental data and make predictions about unobserved quantities …