Adult neurogenesis in neurodegenerative diseases

B Winner, J Winkler - Cold Spring Harbor perspectives in …, 2015 - cshperspectives.cshlp.org
Adult neurogenesis is limited to specific brain regions in the mammalian brain, such as the
hippocampal dentate gyrus and the subventricular zone/olfactory bulb system. Alterations in …

Adult hippocampal neurogenesis in Alzheimer's disease: an overview of human and animal studies with implications for therapeutic perspectives aimed at memory …

S Farioli-Vecchioli, V Ricci, S Middei - Neural Plasticity, 2022 - Wiley Online Library
The mammalian hippocampal dentate gyrus is a niche for adult neurogenesis from neural
stem cells. Newborn neurons integrate into existing neuronal networks, where they play a …

[PDF][PDF] Propofol anesthesia impairs the maturation and survival of adult-born hippocampal neurons.

M Krzisch, S Sultan, J Sandell, K Demeter, L Vutskits… - Anesthesiology, 2013 - serval.unil.ch
BACKGROUND: Adult neurogenesis occurs in the hippocampus of most mammals,
including humans, and plays an important role in hippocampal-dependent learning. This …

[HTML][HTML] Molecular bases of Alzheimer's disease and neurodegeneration: the role of neuroglia

A Luca, C Calandra, M Luca - Aging and disease, 2018 - ncbi.nlm.nih.gov
Neuroglia is an umbrella term indicating different cellular types that play a pivotal role in the
brain, being involved in its development and functional homeostasis. Glial cells are …

Scale invariant disordered nanotopography promotes hippocampal neuron development and maturation with involvement of mechanotransductive pathways

C Schulte, M Ripamonti, E Maffioli… - Frontiers in Cellular …, 2016 - frontiersin.org
The identification of biomaterials which promote neuronal maturation up to the generation of
integrated neural circuits is fundamental for modern neuroscience. The development of …

Transplantation of GABAergic interneuron progenitor attenuates cognitive deficits of Alzheimer's disease model mice

MH Lu, XY Zhao, DE Xu, JB Chen… - Journal of …, 2020 - content.iospress.com
Excitatory (E) and inhibitory (I) balance of neural network activity is essential for normal brain
function and of particular importance to memory. Disturbance of E/I balance contributes to …

Clinical significance of the cognition-related pathogenic proteins in plasma neuronal-derived exosomes among normal cognitive adults over 45 years old with …

Z Chen, FF Chang, L Yao, F Yuan, J Hong… - European Archives of …, 2021 - Springer
Abstract Objectives Exosomal Phospho-Tau-181 (P-T181-tau), Total tau (T-tau), and amyloid-
β peptide 42 (Aβ42) have been proved the capacity for the amnestic mild cognitive …

Physiological, pathological, and engineered cell identity reprogramming in the central nervous system

DK Smith, LL Wang, CL Zhang - Wiley Interdisciplinary Reviews …, 2016 - Wiley Online Library
Multipotent neural stem cells persist in restricted regions of the adult mammalian central
nervous system. These proliferative cells differentiate into diverse neuron subtypes to …

[PDF][PDF] Aus dem Institut für Anatomie II der Heinrich-Heine-Universität Düsseldorf

T Faramarzi - docserv.uni-duesseldorf.de
Zusammenfassung Die Alzheimer-Krankheit ist mit mehr als 50 Millionen Betroffenen
weltweit die am weitesten verbreitete neurodegenerative Erkrankung. Sie stellt daher eine …

Interaction of Aβ dimers with the serotonin receptor 5-HT1β influences adult neurogenesis in tgD mice

T Faramarzi - docserv.uni-duesseldorf.de
Beschreibungen: Alzheimer's disease remains the most common neurodegenerative
disease, affecting more than 50 million people worldwide. This represents an enormous …