Progress in understanding adjuvant immunotoxicity mechanisms

A Batista-Duharte, EB Lindblad, E Oviedo-Orta - Toxicology letters, 2011 - Elsevier
Over the last twenty years research has provided an important insight into the mechanisms
responsible for the immunotoxicity of both local and systemic adverse reactions following the …

[HTML][HTML] Efficacy and safety of immunological adjuvants. Where is the cut-off?

A Batista-Duharte, DT Martínez, IZ Carlos - Biomedicine & …, 2018 - Elsevier
Research over the past several decades has provided insight into the mode of action of
adjuvants. However, the main focus of attention has been the efficacy in the induction of …

Contribution of macrophage migration inhibitory factor to the pathogenesis of dengue virus infection

I Assunçao-Miranda, FA Amaral, FA Bozza… - The FASEB …, 2010 - Wiley Online Library
Dengue fever is an emerging viral disease transmitted by arthropods to humans in tropical
countries. Dengue hemorrhagic fever (DHF) is escalating in frequency and mortality rates …

Macrophage migration inhibitory factor induced by dengue virus infection increases vascular permeability

YC Chuang, HY Lei, HS Liu, YS Lin, TF Fu, TM Yeh - Cytokine, 2011 - Elsevier
Dengue virus (DENV) infection can cause mild dengue fever or severe dengue hemorrhage
fever (DHF) and dengue shock syndrome (DSS). Serum levels of the macrophage migration …

Macrophage migration inhibitory factor regulates neutrophil chemotactic responses in inflammatory arthritis in mice

LL Santos, H Fan, P Hall, D Ngo… - Arthritis & …, 2011 - Wiley Online Library
Objective Macrophage migration inhibitory factor (MIF) facilitates multiple aspects of
inflammatory arthritis, the pathogenesis of which has been significantly linked to the activity …

Dengue virus therapeutic intervention strategies based on viral, vector and host factors involved in disease pathogenesis

LJ Herrero, A Zakhary, ME Gahan, MA Nelson… - Pharmacology & …, 2013 - Elsevier
Dengue virus (DV) is the most widespread arbovirus, being endemic in over 100 countries,
and is estimated to cause 50 million infections annually. Viral factors, such as the genetic …

Macrophage migration inhibitory factor: a multifunctional cytokine in rheumatic diseases

T Kasama, K Ohtsuka, M Sato, R Takahashi… - …, 2010 - Wiley Online Library
Macrophage migration inhibitory factor (MIF) was originally identified in the culture medium
of activated T lymphocytes as a soluble factor that inhibited the random migration of …

[HTML][HTML] Macrophage migration inhibitory factor-knockout mice are long lived and respond to caloric restriction

JM Harper, JE Wilkinson, RA Miller - The FASEB Journal, 2010 - ncbi.nlm.nih.gov
Macrophage migration inhibitory factor (MIF) affects inflammation, glucose homeostasis, and
cellular proliferation in mammals. Previously, we found that MIF was significantly elevated in …

Adyuvantes inmunológicos. Determinantes en el balance eficacia-toxicidad de las vacunas contemporáneas

A Batista-Duharte, M Lastre, O Pérez - Enfermedades Infecciosas y …, 2014 - Elsevier
Para lograr vacunas eficaces y seguras para la prevención de enfermedades infecciosas
aún no controladas o re-emergentes, uno de los aspectos de mayor importancia es contar …

Systemic immunotoxicity reactions induced by adjuvanted vaccines

A Batista-Duharte, D Portuondo, O Perez… - International …, 2014 - Elsevier
Vaccine safety is a topic of concern for the treated individual, the family, the health care
personnel, and the others involved in vaccination programs as recipients or providers …