Candidiasis is a common infection of the skin, oral cavity and esophagus, gastrointestinal
tract, vagina and vascular system of humans. Although most infections occur in patients who …

Candida albicans is the most common fungal pathogen of humans and has developed an
extensive repertoire of putative virulence mechanisms that allows successful colonization …

Pathogenic fungi have become a leading cause of human mortality due to the increasing
frequency of fungal infections in immunocompromised populations and the limited …

The inoculum size effect in the dimorphic fungus Candida albicans results from production of
an extracellular quorum-sensing molecule (QSM). This molecule prevents mycelial …

Farnesol is a quorum-sensing molecule that inhibits filamentation in Candida albicans. Both
filamentation and quorum sensing are deemed to be important factors in C. albicans biofilm …

Our classical perception of microorganisms as unicellular life forms is almost entirely based
on the pure-culture mode of growth; since microbial suspensions can be diluted to a single …

It is widely assumed that the ability of Candida albicans to switch between different
morphologies is required for pathogenesis. However, most virulence studies have used …

Candida albicans is an opportunistic fungal pathogen that is found in the normal
gastrointestinal flora of most healthy humans. However, under certain environmental …

Many fungal pathogens undergo morphological transformations during host invasion.
However, the significance of this for fungal pathogenesis is not clear. Both yeast and hyphal …

We have characterized CaNrg1 from Candida albicans, the major fungal pathogen in
humans. CaNrg1 contains a zinc finger domain that is conserved in transcriptional …