[HTML][HTML] A review of melatonin, its receptors and drugs

M Emet, H Ozcan, L Ozel, M Yayla, Z Halici… - The Eurasian journal …, 2016 - ncbi.nlm.nih.gov
After a Turkish scientist took Nobel Prize due to his contributions to understand clock genes,
melatonin, closely related to these genes, may begin to shine. Melatonin, a hormone …

Reactive oxygen species in the regulation of synaptic plasticity and memory

CA Massaad, E Klann - Antioxidants & redox signaling, 2011 - liebertpub.com
The brain is a metabolically active organ exhibiting high oxygen consumption and robust
production of reactive oxygen species (ROS). The large amounts of ROS are kept in check …

Effects of fluoride on DNA damage, S-phase cell-cycle arrest and the expression of NF-κB in primary cultured rat hippocampal neurons

M Zhang, A Wang, T Xia, P He - Toxicology letters, 2008 - Elsevier
The mechanisms underlying the neurotoxicity of fluorosis still remain obscure. To investigate
DNA damage, cell-cycle distribution and expression of nuclear factor kappa B (NF-κB) …

Melatonin ameliorates cognitive impairment induced by sleep deprivation in rats: role of oxidative stress, BDNF and CaMKII

L Zhang, HQ Zhang, XY Liang, HF Zhang… - Behavioural brain …, 2013 - Elsevier
Sleep deprivation (SD) has been shown to induce oxidative stress which causes cognitive
impairment. Melatonin, an endogenous potent antioxidant, protects neurons from oxidative …

[HTML][HTML] Autism spectrum disorder (ASD): disturbance of the melatonin system and its implications

Z Wu, J Zou, Q Wang, M Naveed, H Bao… - biomedicine & …, 2020 - Elsevier
The molecular mechanisms underlying autism spectrum disorder (ASD) remain elusive,
which limits the management options available in the clinic. Accumulating evidence …

Protective effect of berberine, an isoquinoline alkaloid ameliorates ethanol-induced oxidative stress and memory dysfunction in rats

S Patil, S Tawari, D Mundhada, S Nadeem - … Biochemistry and Behavior, 2015 - Elsevier
Memory impairment induced by ethanol in rats is a consequence of changes in the CNS that
are secondary to impaired oxidative stress and cholinergic dysfunction. Treatment with …

Nattokinase Promotes Post-stroke Neurogenesis and Cognition Recovery via Increasing Circulating Irisin

H Wu, Q Zhang, P Xu, J Chen, L Duan… - Journal of Agricultural …, 2023 - ACS Publications
The therapeutic potential of treatments for post-stroke cognitive impairment (PSCI) is
severely limited by the autonomic regeneration capacity of the adult brain. Nattokinase (NK) …

Drink and think: impact of alcohol on cognitive functions and dementia–evidence of dose-related effects

S Gutwinski, S Schreiter, J Priller, J Henssler… - …, 2018 - thieme-connect.com
Regular alcohol consumption affects cognitive performance and the development of
dementia. So far, findings are contradicting, which might be explained in part by dose …

[HTML][HTML] Melatonin attenuates spatial learning and memory dysfunction in developing rats by suppressing isoflurane-induced endoplasmic reticulum stress via the …

X Fang, Q Han, S Li, A Luo - Heliyon, 2022 - cell.com
Use of the inhalation anesthetic isoflurane may increase the risk of cognitive deficiency and
neurotoxicity after birth. A growing body of evidence suggests that melatonin is an effective …

Long‐term oral administration of melatonin improves spatial learning and memory and protects against cholinergic degeneration in middle‐aged T s65 D n mice, a …

A Corrales, P Martínez, S García, V Vidal… - Journal of pineal …, 2013 - Wiley Online Library
Abstract Ts65Dn mice (TS), the most commonly used model of D own syndrome (DS),
exhibit phenotypic characteristics of this condition. Both TS mice and DS individuals present …