Staphylococcus aureus is a well-known colonizer of the human skin and nose, but also a
human pathogen that causes a wide spectrum of diseases. It is well established that S …

Chronic rhinosinusitis (CRS) is thought to be a multifactorial disease that includes a direct
involvement of bacteria that trigger inflammation and contribute to CRS pathogenesis …

G protein-coupled receptors (GPCRs) are pivotal in mediating diverse physiological and
pathological processes, rendering them promising targets for drug discovery. GPCRs …

Enzymatic reaction-mediated microbial transformation has emerged as a promising
technology with significant potential in various industries. These technologies offer the ability …

The prevalence of multidrug-resistant (MDR) ESKAPE pathogens, including Enterococcus
faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, and …

Staphylococcus aureus (SA) leukocidin ED (LukED) belongs to a family of bicomponent
pore forming toxins that play important roles in SA immune evasion and nutrient acquisition …

Staphylococcus aureus is an opportunistic and versatile pathogen that can cause several
diseases, which range from acute and destructive, to chronic and difficult-to-treat infections …

Staphylococcus aureus causes severe infections such as pneumonia and sepsis depending
on the pore-forming toxin Panton–Valentine leukocidin (PVL). PVL kills and induces …

Many toxins are life-threatening to both animals and humans. However, specific antidotes
are not available for most of those toxins. The molecular mechanisms underlying the …

Genetic screen technology has been applied to study the mechanism of action of bacterial
toxins—a special class of virulence factors that contribute to the pathogenesis caused by …