NLRP3 inflammasome pathway in atherosclerosis: Focusing on the therapeutic potential of non-coding RNAs
SIS Al-Hawary, SA Jasim, RM Romero-Parra… - … -Research and Practice, 2023 - Elsevier
Abstract NLRP3 (NOD-, LRR-, and pyrin domain-containing protein 3) inflammasome
pathway has a critical role in the pathogenesis of atherosclerosis. Activation of this pathway …
pathway has a critical role in the pathogenesis of atherosclerosis. Activation of this pathway …
The application of circulating tumor cell and cell-free DNA liquid biopsies in ovarian cancer
A Balla, J Bhak, O Biró - Molecular and Cellular Probes, 2022 - Elsevier
Ovarian cancer is the deadliest gynecological cancer. 70% of the cases are diagnosed at
late stages with already developed metastases due to the absence of easily noticeable …
late stages with already developed metastases due to the absence of easily noticeable …
WFDC2 promotes spasmolytic polypeptide-expressing metaplasia through the up-regulation of IL33 in response to injury
H Jeong, B Lee, KH Kim, SY Cho, Y Cho, J Park, Y Lee… - Gastroenterology, 2021 - Elsevier
Background & Aims WAP 4-disulfide core domain protein 2 (WFDC2), also known as human
epididymis protein 4, is a small secretory protein that is highly expressed in fibrosis and …
epididymis protein 4, is a small secretory protein that is highly expressed in fibrosis and …
Hypoxia‐induced HE4 in tubular epithelial cells promotes extracellular matrix accumulation and renal fibrosis via NF‐κB
L Zhang, L Liu, M Bai, M Liu, L Wei, Z Yang… - The FASEB …, 2020 - Wiley Online Library
Hypoxia‐induced extracellular matrix (ECM) deposition is an important cause of renal
fibrosis that is triggered by unknown mechanisms. Human epididymis secretory protein 4 …
fibrosis that is triggered by unknown mechanisms. Human epididymis secretory protein 4 …
MicroRNA-140-5p ameliorates the high glucose-induced apoptosis and inflammation through suppressing TLR4/NF-κB signaling pathway in human renal tubular …
J Su, J Ren, H Chen, B Liu - Bioscience Reports, 2020 - portlandpress.com
Hyperglycemia-induced renal tubular cell injury is thought to play a critical role in the
pathogenesis of diabetic nephropathy (DN). However, the role of miRNAs in renal tubular …
pathogenesis of diabetic nephropathy (DN). However, the role of miRNAs in renal tubular …
Human epididymis protein 4 aggravates airway inflammation and remodeling in chronic obstructive pulmonary disease
Y Zhan, J Chen, J Wu, Y Gu, Q Huang, Z Deng… - Respiratory …, 2022 - Springer
Background Chronic obstructive pulmonary disease (COPD) is a progressive disease
characterized by chronic inflammation and airway remodeling. Human epididymis protein 4 …
characterized by chronic inflammation and airway remodeling. Human epididymis protein 4 …
Upregulation of miRNA‑140‑5p inhibits inflammatory cytokines in acute lung injury through the MyD88/NF‑κB signaling pathway by targeting TLR4
Y Yang, D Liu, Y Xi, J Li, B Liu… - Experimental and …, 2018 - spandidos-publications.com
The present study was designed to determine the effect of miR‑140‑5p on acute lung injury
(ALI) and the associated inflammation induced. As a result, miR‑140‑5p expression in mice …
(ALI) and the associated inflammation induced. As a result, miR‑140‑5p expression in mice …
Multimodal analysis of granulocytes, monocytes, and platelets in patients with cystic fibrosis before and after Elexacaftor–Tezacaftor–Ivacaftor treatment
H Schmidt, LM Höpfer, L Wohlgemuth… - Frontiers in …, 2023 - frontiersin.org
Cystic fibrosis (CF) is a monogenetic disease caused by an impairment of the cystic fibrosis
transmembrane conductance regulator (CFTR). CF affects multiple organs and is associated …
transmembrane conductance regulator (CFTR). CF affects multiple organs and is associated …
[HTML][HTML] Elevated serum human epididymis protein 4 is associated with disease severity and worse survival in idiopathic pulmonary fibrosis: a cohort study
M Tian, K Meng, Y Gao, J Zhang, M Xie… - Annals of …, 2022 - ncbi.nlm.nih.gov
Background Elevated expression of human epididymis protein 4 (HE4) was previously
described in connective tissue disease-associated interstitial lung diseases (CTD-ILDs) and …
described in connective tissue disease-associated interstitial lung diseases (CTD-ILDs) and …
Long non-coding RNA PCA3 inhibits lipid accumulation and atherosclerosis through the miR-140-5p/RFX7/ABCA1 axis
ZW Zhao, M Zhang, LX Liao, J Zou, G Wang… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Objective The purpose of this study was to explore the role of long noncoding RNA (lncRNA)
prostate cancer antigen 3 (PCA3) in atherosclerosis and the underlying mechanism …
prostate cancer antigen 3 (PCA3) in atherosclerosis and the underlying mechanism …