Osteoarthritis (OA) is a common degenerative disease characterized by the destruction of
articular cartilage and chronic inflammation of surrounding tissues. Matrix metalloproteinase …

Inflammation is a complicated biological and pathophysiological cascade of responses to
infections and injuries, and inflammatory mechanisms are closely related to many diseases …

Osteoarthritis is a prevalent and debilitating disease that involves pathological contributions
from numerous joint tissues and cells. The joint is a challenging arena for drug delivery …

Osteoarthritis (OA) is a prevalent disease of most mammalian species and is a significant
cause of welfare and economic morbidity in affected individuals and populations. In vitro …

Introduction Osteoarthritis (OA) is a common disease worldwide leading to significant
morbidity. The underlying disease process is multifactorial however there is increasing focus …

Osteoarthritis (OA) is a common degenerative joint disorder, which involves articular
cartilage degeneration as well as joint inflammatory reactions. The recent studies have …

Chondrocytes communicate with each other mainly via diffusible signals rather than direct
cell‐to‐cell contact. The chondrogenic differentiation of mesenchymal stem cells (MSCs) is …

Epigenetic abnormalities are part of the pathogenetic alterations involved in the
development of rheumatic disorders. In this context, the main musculoskeletal cell lineages …

Osteoarthritis (OA) is a degenerative whole joint disease, for which no preventative or
therapeutic biological interventions are available. This is likely due to the fact that OA …

Aging is a natural process characterized by the declining ability of the different organs and
tissues to respond to stress, increasing homeostatic imbalance and risk of disease …