Conrad Waddington's theory of epigenetic landscape epitomize the process of cell fate and
cellular decision-making during development. Wherein the epigenetic code maintains …

Cancer is a complex disease and cancer development takes 10–50 years involving
epigenetics. Evidence suggests that approximately 80% of human cancers are linked to …

Bladder cancer (BLCA) is a common malignant cancer, and it is the most common
genitourinary cancer in the world. The recurrence rate is the highest of all cancers, and the …

Prostate cancer is a highly heterogeneous disease. Progression on androgen deprivation
therapy (ADT) to castration-resistant (CRPC), or neuroendocrine prostate cancer (NEPC), is …

Epigenetic modifications via DNA methylation and long non-coding RNAs (lncRNAs) have
been identified in bladder cancer (BC). However, DNA methylation of lncRNAs involved in …

Prostate cancer remains a major public health problem and the second leading cause of
cancer-related deaths in men in the United States. The present study aims to understand the …

Background The current study aimed to explore the association between two epigenomic
components, miRNA and DNA methylation, in bladder cancer (BC). Methods Eight paired …

The derivation of induced pluripotent stem cells (iPSCs) has opened doors for numerous
applications for which limited human cell sources were available. However, their use has …

The search for a pan-cancer prognostic biomarker with potential therapeutic implications is a
challenging facet of cancer research. Here, I utilize several publicly available bioinformatics …

Chronic pain is a common clinical symptom resulting from numerous tissue injuries or
disorders and often associated with altered functional and structural plasticity in tissues …