Thermally dimorphic human fungal pathogens—polyphyletic pathogens with a convergent pathogenicity trait

A Sil, A Andrianopoulos - Cold Spring …, 2015 - perspectivesinmedicine.cshlp.org
Fungi are adept at changing their cell shape and developmental program in response to
signals in their surroundings. Here we focus on a group of evolutionarily related fungal …

Physical methods for genetic transformation of fungi and yeast

AL Rivera, D Magana-Ortiz, M Gomez-Lim… - Physics of life …, 2014 - Elsevier
The production of transgenic fungi is a routine process. Currently, it is possible to insert
genes from other fungi, viruses, bacteria and even animals, albeit with low efficiency, into the …

Molecular characterization of siderophore biosynthesis in Paracoccidioides brasiliensis

MG Silva, JS De Curcio, MG Silva-Bailão, RM Lima… - IMA fungus, 2020 - Springer
Iron is an essential nutrient for all organisms. For pathogenic fungi, iron is essential for the
success of infection. Thus, these organisms have developed high affinity iron uptake …

Identification and Analysis of the Role of Superoxide Dismutases Isoforms in the Pathogenesis of Paracoccidioides spp.

D Tamayo, JF Muñoz, Á Lopez, M Urán… - PLoS Neglected …, 2016 - journals.plos.org
The ability of Paracoccidioides to defend itself against reactive oxygen species (ROS)
produced by host effector cells is a prerequisite to survive. To counteract these radicals …

Hemoglobin Uptake by Paracoccidioides spp. Is Receptor-Mediated

EFLC Bailão, JA Parente, LL Pigosso… - PLoS neglected …, 2014 - journals.plos.org
Iron is essential for the proliferation of fungal pathogens during infection. The availability of
iron is limited due to its association with host proteins. Fungal pathogens have evolved …

Agrobacterium-Mediated Transformation of Yeast and Fungi

PJJ Hooykaas, GPH van Heusden, X Niu… - … Biology: From Basic …, 2018 - Springer
Two decades ago, it was discovered that the well-known plant vector Agrobacterium
tumefaciens can also transform yeasts and fungi when these microorganisms are co …

New insights into a complex fungal pathogen: the case of Paracoccidioides spp.

A Gonzalez, O Hernandez - Yeast, 2016 - Wiley Online Library
Paracoccidioidomycosis is a systemic mycosis endemic to Latin America, with
Paracoccidioides brasiliensis and P. lutzii being the causal agents of this disorder. Several …

Pseudomonas aeruginosa inhibits the growth of Scedosporium aurantiacum, an opportunistic fungal pathogen isolated from the lungs of cystic fibrosis patients

J Kaur, BP Pethani, S Kumar, M Kim, A Sunna… - Frontiers in …, 2015 - frontiersin.org
The filamentous fungus Scedosporium aurantiacum and the bacterium Pseudomonas
aeruginosa are opportunistic pathogens isolated from lungs of the cystic fibrosis (CF) …

Interactions of Paracoccidioides brasiliensis with host cells: recent advances

MJS Mendes-Giannini, JL Monteiro da Silva… - Mycopathologia, 2008 - Springer
Host-fungal interactions are inherently complex and dynamic. In order to identify new
microbial targets and develop more effective anti-fungal therapies, it is important to …

Alternative Oxidase Mediates Pathogen Resistance in Paracoccidioides brasiliensis Infection

O Hernández Ruiz, A Gonzalez… - PLoS neglected …, 2011 - journals.plos.org
Background Paracoccidioides brasiliensis is a human thermal dimorphic pathogenic fungus.
Survival of P. brasiliensis inside the host depends on the adaptation of this fungal pathogen …