Reactive oxygen species in macrophages: sources and targets
M Canton, R Sánchez-Rodríguez, I Spera… - Frontiers in …, 2021 - frontiersin.org
Reactive oxygen species (ROS) are fundamental for macrophages to eliminate invasive
microorganisms. However, as observed in nonphagocytic cells, ROS play essential roles in …
microorganisms. However, as observed in nonphagocytic cells, ROS play essential roles in …
Monoamine oxidases in age-associated diseases: New perspectives for old enzymes
Population aging is one of the most significant social changes of the twenty-first century. This
increase in longevity is associated with a higher prevalence of chronic diseases, further …
increase in longevity is associated with a higher prevalence of chronic diseases, further …
[HTML][HTML] Monoamine oxidases: A missing link between mitochondria and inflammation in chronic diseases?
L Beucher, C Gabillard-Lefort, OR Baris, J Mialet-Perez - Redox Biology, 2024 - Elsevier
The role of mitochondria spans from the regulation of the oxidative phosphorylation, cell
metabolism and survival/death pathways to a more recently identified function in chronic …
metabolism and survival/death pathways to a more recently identified function in chronic …
Mechanisms of dopamine oxidation and Parkinson's disease
J Segura-Aguilar, I Paris - Handbook of neurotoxicity, 2022 - Springer
Dopamine's ability to oxidize to aminochrome explains why this molecule may be a
neurotoxic compound that induces toxicity in both cell lines and animal models …
neurotoxic compound that induces toxicity in both cell lines and animal models …
Fatty acids and their lipid mediators in the induction of cellular apoptosis in cancer cells
P Biswas, C Datta, P Rathi, A Bhattacharjee - Prostaglandins & Other Lipid …, 2022 - Elsevier
The oxygenation of polyunsaturated fatty acids such as arachidonic and linoleic acid
through enzymes like lipoxygenases (LOXs) are common and often leads to the production …
through enzymes like lipoxygenases (LOXs) are common and often leads to the production …
Induction of monoamine oxidase A-mediated oxidative stress and impairment of NRF2-antioxidant defence response by polyphenol-rich fraction of Bergenia ligulata …
Prostate cancer (PCa) is a major cause of mortality and morbidity in men. Available
therapies yield limited outcome. We explored anti-PCa activity in a polyphenol-rich fraction …
therapies yield limited outcome. We explored anti-PCa activity in a polyphenol-rich fraction …
Ultrasound neuromodulation of the spleen has time-dependent anti-inflammatory effect in a pneumonia model
Interfaces between the nervous and immune systems have been shown essential for the
coordination and regulation of immune responses. Non-invasive ultrasound stimulation …
coordination and regulation of immune responses. Non-invasive ultrasound stimulation …
IL-13 and the hydroperoxy fatty acid 13 (S) HpODE play crucial role in inducing an apoptotic pathway in cancer cells involving MAO-A/ROS/p53/p21 signaling axis
This study depicted the effect of IL-13 and 13 (S) HpODE (the endogenous product during IL-
13 activation) in the process of cancer cell apoptosis. We examined the role of both IL-13 …
13 activation) in the process of cancer cell apoptosis. We examined the role of both IL-13 …
Design, synthesis, and biological evaluation of novel MAO-A inhibitors targeting lung cancer
Lung cancer is one of the most common causes of cancer-related deaths worldwide.
Monoamine Oxidase-A (MAO-A) enzyme mediates the production of reactive oxygen …
Monoamine Oxidase-A (MAO-A) enzyme mediates the production of reactive oxygen …
Halting colorectal cancer metastasis via novel dual nanomolar MMP-9/MAO-A quinoxaline-based inhibitors; design, synthesis, and evaluation
Abstract Matrix metalloproteinase-9 (MMP-9) and monoamine oxidase-A (MAO-A) are
central signaling nodes in CRC and promotors of distant metastasis associated with high …
central signaling nodes in CRC and promotors of distant metastasis associated with high …