Ketamine is a noncompetitive antagonist of N-methyl-d-asparate (NMDA) receptor and has
been long used as an anesthetic agent in humans and veterinary medicine. The present …

Ketamine an N-methyl-D-aspartate (NMDA) receptor blocking agent and a dissociative
anesthetic with neurostimulatory side effects. In recent years, multiple research trials as well …

Promising renal replacement therapies include the development of a bioartificial kidney
using functional human kidney cell models. In this study, human conditionally immortalized …

Even prior to the COVID-19 pandemic, rates of ambulatory surgeries and ambulatory
patients presenting with substance use disorder were increasing, and the end of lockdown …

Active cell migration and invasion is a peculiar feature of glioma that makes this tumor able
to rapidly infiltrate into the surrounding brain tissue. In our recent work, we identified a novel …

Introduction Fibrosis of renal tubules is the final common pathway in diabetic nephropathy
and develops in the face of tubular injury and fibroblast activation. Aberrant connexin 43 …

The tubular epithelium may be intrinsically involved in promoting kidney injury by junctional
instability, epithelial‐mesenchymal transition (EMT) and extracellular matrix remodelling. In …

Bladder wall fibrosis is a major complication of ketamine-induced cystitis (KC), but the
underlying pathogenesis is poorly understood. The aim of the present study was to elucidate …

Ketamine cystitis (KC) is a chronic bladder inflammation leading to urinary urgency,
frequency, and pain. The pathogenesis of KC is complicated and involves multiple tissue …

Ketamine is a widely-used anesthetic in the field of pediatrics and obstetrics. Multiple studies
have revealed that ketamine causes neurotoxicity in developing animals. However, further …