Autism spectrum disorder (ASD) is a prevalent and complex neurodevelopmental disorder
which has strong genetic basis. Despite the rapidly rising incidence of autism, little is known …

The current diagnostic practices are linked to a 20-fold increase in the reported prevalence
of ASD over the last 30 years. Fragmenting the autism phenotype into dimensional “autistic …

Autism spectrum disorder (ASD) is a neurodevelopmental impairment characterized by
deficits in social interaction skills, impaired communication, and repetitive and restricted …

Progress in understanding the genetic etiology of autism spectrum disorders (ASD) has
fueled remarkable advances in our understanding of its potential neurobiological …

Genetics studies of autism spectrum disorder (ASD) have identified several risk genes that
are key regulators of synaptic plasticity. Indeed, many of the risk genes that have been …

Cerebellar research has focused principally on adult motor function. However, the
cerebellum also maintains abundant connections with nonmotor brain regions throughout …

Imbalances between excitation and inhibition in synaptic transmission and neural circuits
have been implicated in autism spectrum disorders. Excitation and inhibition imbalances are …

The human cerebellum has a protracted developmental timeline compared with the
neocortex, expanding the window of vulnerability to neurological disorders. As the …

A fundamental challenge in developing treatments for autism spectrum disorders is the
heterogeneity of the condition. More than one hundred genetic mutations confer high risk for …

Autism spectrum disorder (ASD) is a pervasive neurodevelopmental syndrome with a high
human and economic burden. The pathophysiology of ASD is largely unclear, thus …