The neurobiology of sleep and substance abuse interconnects, such that alterations in one
process have consequences for the other. Acute exposure to drugs of abuse disrupts sleep …

Sleep health is an important factor across several physical and mental health disorders, and
a growing scientific consensus has identified sleep as a critical component of opioid use …

There is a complex relationship among opioids, sleep and daytime function. Patients and
medical providers should be aware that chronic opioid therapy can alter sleep architecture …

Sleep is an evolutionarily conserved process and is important for rest and recovery of
various biological functions. Sleep and alertness alterations, function as contributing …

It is generally accepted that chronic opioid use is associated with structural and functional
changes in the human brain that lead to an enhancement of impulsive behavior for …

Background Novel strategies are needed to curb the opioid overdose epidemic. Smart home
sensors have been successfully deployed as digital biomarkers to monitor health conditions …

Preclinical models of addictive drugs have been developed for decades to model aspects of
the clinical experience in substance use disorders (SUDs). These include passive exposure …

The electroencephalogram (EEG) provides an objective, neural correlate of consciousness.
Opioid receptors modulate mammalian neuronal excitability, and this fact was used to …

Study Objectives: Individuals with opioid use disorder (OUD) may experience worsening
sleep quality over time, and a subset of individuals may have sleep disturbances that …

Sleep is very important for our physical and mental health. Sleep disturbances increase risk
of substance use disorders as well as risk of onset and worsening of medical and other …