Luciferase-based biosensors in the era of the COVID-19 pandemic
T Azad, HJ Janse van Rensburg, J Morgan… - ACS nanoscience …, 2021 - ACS Publications
Luciferase-based biosensors have a wide range of applications and assay formats,
including their relatively recent use in the study of viruses. Split luciferase, bioluminescence …
including their relatively recent use in the study of viruses. Split luciferase, bioluminescence …
Advancing Luciferase-Based Antibody Immunoassays to Next-Generation Mix and Read Testing
PD Burbelo, Y Ji, MJ Iadarola - Biosensors, 2023 - mdpi.com
Antibody measurements play a central role in the diagnosis of many autoimmune and
infectious diseases. One antibody detection technology, Luciferase Immunoprecipitation …
infectious diseases. One antibody detection technology, Luciferase Immunoprecipitation …
Engineering a NanoBiT biosensor for detecting angiotensin-converting enzyme-2 (hACE2) interaction with SARS-CoV-2 spike protein and screening the inhibitors to …
CH Lin, XR Yang, MW Lin, HJ Chang, CH Lee… - Biosensors and …, 2024 - Elsevier
Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is facilitated
by its trimeric surface spike protein, which binds to the human angiotensin-converting …
by its trimeric surface spike protein, which binds to the human angiotensin-converting …
Identification of FDA-approved bifonazole as a SARS-CoV-2 blocking agent following a bioreporter drug screen
Z Taha, R Arulanandam, G Maznyi, E Godbout… - Molecular Therapy, 2022 - cell.com
We established a split nanoluciferase complementation assay to rapidly screen for inhibitors
that interfere with binding of the receptor binding domain (RBD) of the severe acute …
that interfere with binding of the receptor binding domain (RBD) of the severe acute …
Advanced high-throughput biosensor-based diagnostic approaches for detection of severe acute respiratory syndrome-coronavirus-2
Given the global Coronavirus disease-2019 (COVID-19) pandemic, the transmission, and
mortality rate increased drastically and affected the healthcare, financial sectors, and …
mortality rate increased drastically and affected the healthcare, financial sectors, and …
Thermodynamically coupled biosensors for detecting neutralizing antibodies against SARS-CoV-2 variants
We designed a protein biosensor that uses thermodynamic coupling for sensitive and rapid
detection of neutralizing antibodies against severe acute respiratory syndrome coronavirus …
detection of neutralizing antibodies against severe acute respiratory syndrome coronavirus …
Establishment of the Foot-and-Mouth Disease Virus Type Asia1 Expressing the HiBiT Protein: A Useful Tool for a NanoBiT Split Luciferase Assay
G Cho, H Kim, DW Kim, SY Hwang, JH Hwang… - Viruses, 2024 - mdpi.com
Foot-and-mouth disease virus (FMDV) is a highly contagious virus that affects cloven-hoofed
animals and causes severe economic losses in the livestock industry. Given that this high …
animals and causes severe economic losses in the livestock industry. Given that this high …
Surrogate test performance for SARS‐CoV‐2 neutralizing antibodies (nAbs) for convalescent plasma (CCP): how useful could they be?
S Wendel, R Fachini, RCL Fontão‐Wendel… - …, 2021 - Wiley Online Library
Background COVID‐19 high‐titer CCP selection is a concern, because neutralizing antibody
(nAb) testing requires sophisticated labs and methods. Surrogate tests are an alternative for …
(nAb) testing requires sophisticated labs and methods. Surrogate tests are an alternative for …
Detection of SARS-CoV-2 receptor-binding domain antibody using a HiBiT-based bioreporter
R Rezaei, A Surendran, R Singaravelu… - JoVE (Journal of …, 2021 - jove.com
The emergence of the COVID-19 pandemic has increased the need for better serological
detection methods to determine the epidemiologic impact of severe acute respiratory …
detection methods to determine the epidemiologic impact of severe acute respiratory …
Detection of antibodies neutralizing historical and emerging SARS-CoV-2 strains using a thermodynamically coupled de novo biosensor system
With global vaccination efforts against SARS-CoV-2 underway, there is a need for rapid
quantification methods for neutralizing antibodies elicited by vaccination and …
quantification methods for neutralizing antibodies elicited by vaccination and …