Arrestins are a small family of four proteins in most vertebrates that bind hundreds of
different G protein-coupled receptors (GPCRs). Arrestin binding to a GPCR has at least three …

G protein-coupled receptors (GPCRs) mediate diverse signaling in part through interaction
with arrestins, whose binding promotes receptor internalization and signaling through G …

β3‐Adrenoceptor agonists have proven useful in the treatment of overactive bladder
syndrome, but it is not known whether their efficacy during chronic administration may be …

The stabilization of different active conformations of G protein–coupled receptors is thought
to underlie the varying efficacies of biased and balanced agonists. Here, profiling the …

β-Arrestins are key regulators and signal transducers of G protein–coupled receptors
(GPCRs). The interaction between receptors and β-arrestins is generally believed to require …

β‐arrestin2, a member of the arrestin family, mediates the desensitization and internalization
of most G protein‐coupled receptors (GPCRs) and functions as a scaffold protein in …

Analysis of protein–protein interactions in living cells by protein micropatterning is currently
limited to the spatial arrangement of transmembrane proteins and their corresponding …

Abstract GPR27, GPR85 and GPR173 constitute a small family of G protein-coupled
receptors (GPCR) that share the distinctive characteristics of being highly conserved …

The G protein-coupled receptors (GPCRs) are plasma membrane proteins that function as
sensors of changes in the internal and external milieux and play essential roles in health …

Protein micropatterning is a powerful tool for spatial arrangement of transmembrane and
intracellular proteins in living cells. The restriction of one interaction partner (the bait, eg, the …