Key determinants of success in fecal microbiota transplantation: From microbiome to clinic

S Porcari, N Benech, M Valles-Colomer, N Segata… - Cell host & …, 2023 - cell.com
Fecal microbiota transplantation (FMT) has achieved satisfactory results in preventing the
recurrence of Clostridioides difficile infection, but these positive outcomes have only been …

The influence of gut microbiota alteration on age-related neuroinflammation and cognitive decline

AS Alsegiani, ZA Shah - Neural Regeneration Research, 2022 - journals.lww.com
Recent emerging research on intestinal microbiota and its contribution to the central nervous
system during health and disease has attracted significant attention. Age-related intestinal …

Fecal microbiota transplantation in alcohol-associated acute-on-chronic liver failure: an open-label clinical trial

A Sharma, A Roy, M Premkumar, N Verma… - Hepatology …, 2022 - Springer
Background Severe alcoholic hepatitis (SAH) presenting as acute-on-chronic liver failure
(ACLF) carries a high short-term mortality. Alteration of gut microbiota is a crucial component …

Sex-specific post-inflammatory dysbiosis mediates chronic visceral pain in colitis

MJ Arzamendi, YB Habibyan, M Defaye, A Shute… - Gut …, 2024 - Taylor & Francis
Background Despite achieving endoscopic remission, over 20% of inflammatory bowel
disease (IBD) patients experience chronic abdominal pain. Visceral pain and the …

Facts and hopes for gut microbiota interventions in cancer immunotherapy

D Davar, HM Zarour - Clinical Cancer Research, 2022 - AACR
Immune checkpoint inhibitors (ICI) targeting cytotoxic T-lymphocyte–associated antigen 4
(CTLA-4) and programmed death 1 (PD-1) proteins transformed the management of …

Fecal microbial transplants as investigative tools in cancer

MS Bohm, AV Ramesh, JF Pierre… - American Journal …, 2024 - journals.physiology.org
The gut microbiome plays a critical role in the development, progression, and treatment of
cancer. As interest in microbiome-immune-cancer interactions expands, the prevalence of …

A comparison of methods of gut microbiota transplantation for preclinical studies

J Mingaila, A Atzeni, A Burokas - International journal of molecular …, 2023 - mdpi.com
The experimental details reported in preclinical fecal microbiota transplantation (FMT)
protocols are highly inconsistent, variable, and/or incomplete. We therefore evaluated FMT …

A synbiotic of Anaerostipes caccae and lactulose prevents and treats food allergy in mice

LA Hesser, AA Puente, J Arnold, E Ionescu, A Mirmira… - Cell Host & Microbe, 2024 - cell.com
Depletion of beneficial microbes by modern lifestyle factors correlates with the rising
prevalence of food allergies. Re-introduction of allergy-protective bacteria may be an …

A study on the method and effect of the construction of a humanized mouse model of fecal microbiota transplantation

Y Wang, Z Zhang, B Liu, C Zhang, J Zhao, X Li… - Frontiers in …, 2022 - frontiersin.org
The gestation period is critical for the health of the mother and fetus. Malnutrition or over
nutrition during pregnancy may cause gestational diseases that can result in adverse …

Dosing a synbiotic of human milk oligosaccharides and B. infantis leads to reversible engraftment in healthy adult microbiomes without antibiotics

JE Button, CA Autran, AL Reens, CM Cosetta… - Cell Host & Microbe, 2022 - cell.com
Predictable and sustainable engraftment of live biotherapeutic products into the human gut
microbiome is being explored as a promising way to modulate the human gut microbiome …