From bulk, single-cell to spatial RNA sequencing

X Li, CY Wang - International journal of oral science, 2021 - nature.com
RNA sequencing (RNAseq) can reveal gene fusions, splicing variants, mutations/indels in
addition to differential gene expression, thus providing a more complete genetic picture than …

miRNAs in cancer (review of literature)

B Smolarz, A Durczyński, H Romanowicz… - International journal of …, 2022 - mdpi.com
MicroRNAs (miRNAs) are short, noncoding, single-stranded RNA molecules that regulate
gene expression at the post-transcriptional level by binding to mRNAs. miRNAs affect the …

Changing technologies of RNA sequencing and their applications in clinical oncology

Y Wang, M Mashock, Z Tong, X Mu, H Chen… - Frontiers in …, 2020 - frontiersin.org
RNA sequencing (RNAseq) is one of the most commonly used techniques in life sciences,
and has been widely used in cancer research, drug development, and cancer diagnosis and …

High expression levels of pyrimidine metabolic rate–limiting enzymes are adverse prognostic factors in lung adenocarcinoma: A study based on The Cancer Genome …

H Wang, X Wang, L Xu, J Zhang, H Cao - Purinergic signalling, 2020 - Springer
Reprogramming of metabolism is described in many types of cancer and is associated with
the clinical outcomes. However, the prognostic significance of pyrimidine metabolism …

[HTML][HTML] A comparative analysis of single-cell transcriptomic technologies in plants and animals

VR Netla, H Shinde, G Kumar, A Dudhate, JC Hong… - Current Plant …, 2023 - Elsevier
The development of sequencing methods has resulted in the investigation of many
unexplored research areas. Among the different sequencing methods, single-cell …

miR-10a-5p and miR-29b-3p as extracellular vesicle-associated prostate cancer detection markers

TS Worst, C Previti, K Nitschke, N Diessl, JC Gross… - Cancers, 2019 - mdpi.com
Extracellular vesicles (EVs) are shed by many different cell types. Their nucleic acids content
offers new opportunities for biomarker research in different solid tumors. The role of EV RNA …

Potential of miR-181a-5p and miR-630 as clinical biomarkers in NSCLC

J Simiene, D Dabkeviciene, D Stanciute… - BMC cancer, 2023 - Springer
Background The development of drug resistance and high mortality rates are the major
problems observed in non-small cell lung cancer (NSCLC). Biomarkers indicating and …

LncRNA LINC00511 promotes COL1A1-mediated proliferation and metastasis by sponging miR-126-5p/miR-218-5p in lung adenocarcinoma

Y Wang, X Mei, W Song, C Wang, X Qiu - BMC Pulmonary Medicine, 2022 - Springer
Background Lung adenocarcinoma (LUAD) is currently the leading cause of cancer-related
death worldwide. Long noncoding RNAs (lncRNAs) play key roles in tumor occurrence and …

Long noncoding RNA SNHG5 induces the NF-κB pathway by regulating miR-181c-5p/CBX4 axis to promote the progression of non-small cell lung cancer

S Kang, C Ou, A Yan, K Zhu, R Xue, Y Zhang… - Archivos de …, 2023 - Elsevier
Objective Explorations have been progressing in decoding the mechanism of non-small cell
lung cancer (NSCLC). However, long noncoding RNA small nucleolar RNA host gene …

[HTML][HTML] Downregulation of LINC00665 suppresses the progression of lung adenocarcinoma via regulating miR-181c-5p/ZIC2 axis

W Wei, X Zhao, J Liu, Z Zhang - Aging (albany NY), 2021 - ncbi.nlm.nih.gov
Long non-coding RNA (lncRNA) LINC00665 was demonstrated to be upregulated in lung
adenocarcinoma (LUAD) and target miR-181c-5p. ZIC2, which is upregulated in LUAD …