Identification of differentially methylated loci using wavelet-based functional mixed models
Motivation: DNA methylation is a key epigenetic modification that can modulate gene
expression. Over the past decade, a lot of studies have focused on profiling DNA …
expression. Over the past decade, a lot of studies have focused on profiling DNA …
A stationary wavelet entropy-based clustering approach accurately predicts gene expression
Studying epigenetic landscapes is important to understand the condition for gene regulation.
Clustering is a useful approach to study epigenetic landscapes by grouping genes based on …
Clustering is a useful approach to study epigenetic landscapes by grouping genes based on …
Parameter estimation based on scale-dependent algebraic expressions and scale-space fitting
We present our results of applying wavelet theory to the classic problem of estimating the
unknown parameters of a model function subject to noise. The model function studied in this …
unknown parameters of a model function subject to noise. The model function studied in this …
Heavy-tailed noise suppression and derivative wavelet scalogram for detecting DNA copy number aberrations
Most existing array comparative genomic hybridization (array CGH) data processing
methods and evaluation models assumed that the probability density function (pdf) of noise …
methods and evaluation models assumed that the probability density function (pdf) of noise …
[HTML][HTML] Function-on-function regression for the identification of epigenetic regions exhibiting windows of susceptibility to environmental exposures
M Zemplenyi, MJ Meyer, A Cardenas… - The annals of applied …, 2021 - ncbi.nlm.nih.gov
The ability to identify time periods when individuals are most susceptible to exposures as
well as the biological mechanisms through which these exposures act is of great public …
well as the biological mechanisms through which these exposures act is of great public …
Dynamic epigenetic mode analysis using spatial temporal clustering
Background Differentiation of human embryonic stem cells requires precise control of gene
expression that depends on specific spatial and temporal epigenetic regulation. Recently …
expression that depends on specific spatial and temporal epigenetic regulation. Recently …
Nucleosome positioning and its role in gene regulation in yeast
H Liu, W Ma, J Xie, H Li, K Luo, D Luo… - The Yeast Role in …, 2018 - books.google.com
Nucleosome, composed of a 147-bp segment of DNA helix wrapped around a histone
protein octamer, serves as the basic unit of chromatin. Nucleosome positioning refers to the …
protein octamer, serves as the basic unit of chromatin. Nucleosome positioning refers to the …
A wavelet approach to detect enriched regions and explore epigenomic landscapes
Epigenetic landscapes represent how cells regulate gene activity. To understand their effect
on gene regulation, it is important to detect their occupancy in the genome. Unlike …
on gene regulation, it is important to detect their occupancy in the genome. Unlike …
ATAC-seq signal processing and recurrent neural networks can identify RNA polymerase activity
Nascent transcription assays are the current gold standard for identifying regions of active
transcription, including markers for functional transcription factor (TF) binding. Here we …
transcription, including markers for functional transcription factor (TF) binding. Here we …
Gaussian derivative wavelets identify dynamic changes in histone modification
Epigenetic landscapes reveal how cells regulate genes in a cell-type or condition specific
manner. Genome-wide surveys using histone modification showed cell-type specific …
manner. Genome-wide surveys using histone modification showed cell-type specific …