Structural hippocampal abnormalities are common in many neurological and psychiatric
disorders, and variation in hippocampal measures is related to cognitive performance and …

Background Major depressive disorder (MDD) is a severe and pervasive psychiatric
condition with a lifetime prevalence of 15–25%. Numerous Magnetic Resonance Imaging …

Background Increases in the volume of the amygdala and hippocampus after
electroconvulsive therapy (ECT) are among the most robust effects known to the brain …

The amygdala is an evolutionarily conserved core structure in emotion processing and one
of the key regions of interest in affective neuroscience. Results of neuroimaging studies …

The hippocampus and amygdala have been implicated in the pathophysiology and
treatment of major depressive disorder (MDD). Preclinical models suggest that stress-related …

Background: Hippocampal disturbances are important in the pathophysiology of both
schizophrenia and major depressive disorder (MDD). Imaging studies have shown selective …

Antidepressant doses of ketamine rapidly facilitate synaptic plasticity and modify neuronal
function within prefrontal and hippocampal circuits. However, most studies have …

Morphological changes in the hippocampal, thalamic, and amygdala subfields have been
suggested to form part of the pathophysiology of major depressive disorder (MDD) …

Specific subfields within the hippocampus have shown vulnerability to chronic stress,
highlighting the importance of looking regionally within the hippocampus to understand the …

BackgroundLate-life depression has been associated with volume changes of the
hippocampus. However, little is known about its association with specific hippocampal …