Leukocyte trafficking to the lungs and beyond: lessons from influenza for COVID-19
R Alon, M Sportiello, S Kozlovski, A Kumar… - Nature Reviews …, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
coronavirus disease 2019 (COVID-19). Understanding of the fundamental processes …
coronavirus disease 2019 (COVID-19). Understanding of the fundamental processes …
Pathogenesis of respiratory viral and fungal coinfections
Individuals suffering from severe viral respiratory tract infections have recently emerged as
“at risk” groups for developing invasive fungal infections. Influenza virus is one of the most …
“at risk” groups for developing invasive fungal infections. Influenza virus is one of the most …
[HTML][HTML] Implications of sex differences in immunity for SARS-CoV-2 pathogenesis and design of therapeutic interventions
MJ Bunders, M Altfeld - Immunity, 2020 - cell.com
Men present more frequently with severe manifestations of coronavirus disease 2019
(COVID-19) and are at higher risk for death. The underlying mechanisms for these …
(COVID-19) and are at higher risk for death. The underlying mechanisms for these …
A distinct function of regulatory T cells in tissue protection
Regulatory T (Treg) cells suppress immune responses to a broad range of non-microbial
and microbial antigens and indirectly limit immune inflammation-inflicted tissue damage by …
and microbial antigens and indirectly limit immune inflammation-inflicted tissue damage by …
Mesenchymal stem cell-derived extracellular vesicles attenuate influenza virus-induced acute lung injury in a pig model
M Khatri, LA Richardson, T Meulia - Stem cell research & therapy, 2018 - Springer
Background Mesenchymal stem (stromal) cells (MSCs) mediate their immunoregulatory and
tissue repair functions by secreting paracrine factors, including extracellular vesicles (EVs) …
tissue repair functions by secreting paracrine factors, including extracellular vesicles (EVs) …
Influenza virus-induced lung injury: pathogenesis and implications for treatment
S Herold, C Becker, KM Ridge… - European Respiratory …, 2015 - Eur Respiratory Soc
The influenza viruses are some of the most important human pathogens, causing substantial
seasonal and pandemic morbidity and mortality. In humans, infection of the lower respiratory …
seasonal and pandemic morbidity and mortality. In humans, infection of the lower respiratory …
Production of IL-10 by CD4+ regulatory T cells during the resolution of infection promotes the maturation of memory CD8+ T cells
Memory CD8+ T cells are critical for host defense upon reexposure to intracellular
pathogens. We found that interleukin 10 (IL-10) derived from CD4+ regulatory T cells (Treg …
pathogens. We found that interleukin 10 (IL-10) derived from CD4+ regulatory T cells (Treg …
Host recovery from respiratory viral infection
Emerging and re-emerging respiratory viral infections pose a tremendous threat to human
society, as exemplified by the ongoing COVID-19 pandemic. Upon viral invasion of the …
society, as exemplified by the ongoing COVID-19 pandemic. Upon viral invasion of the …
Regulatory T cell-derived IL-1Ra suppresses the innate response to respiratory viral infection
JW Griffith, LD Faustino, VI Cottrell, K Nepal… - Nature …, 2023 - nature.com
Regulatory T (Treg) cell modulation of adaptive immunity and tissue homeostasis is well
described; however, less is known about Treg cell-mediated regulation of the innate immune …
described; however, less is known about Treg cell-mediated regulation of the innate immune …
Dynamic natural killer cell and T cell responses to influenza infection
Influenza viruses have perplexed scientists for over a hundred years. Yearly vaccines limit
their spread, but they do not prevent all infections. Therapeutic treatments for those …
their spread, but they do not prevent all infections. Therapeutic treatments for those …