The 1, 4-conjugate addition reaction between activated alkynes or acetylenic Michael
acceptors and nucleophiles (ie, the nucleophilic Michael reaction) is a historically useful …

Pyrazole is an essential structural component of many pharmaceuticals and agrochemicals.
The synthesis of pyrazoles has been a subject of intense research for several decades …

A new metal-free synthesis of pyrrole from allyl ketone and amine has been established. The
reaction proceeds via an thiolative activation of the C–C double bond with dimethyl …

Great progress has been made in the tandem annulation of enynes in the past few years.
This review only presents the corresponding reactions of 1, 3-enyne structural motifs to …

This review describes the efforts in the synthesis of pyrrole derivatives using the reaction of
alkynes with nitrogen‐compounds under transition metal‐catalyzed and metal‐free …

A two-step Pd-catalyzed (3+ 2) cycloaddition/HNO2 elimination reaction sequence has been
developed to give novel cyclic 1, 3-dien-5-yne systems from Pd-stabilized zwitterionic 1, 3 …

A novel chromatography-and catalyst-free methodology has been developed for the
synthesis of poly substituted pyrrole in good yields via a multicomponent reaction of …

A copper-catalyzed cascade cyclization of enynes with Togni's reagent, carbon dioxide, and
amines has been successfully developed. The reaction provides a direct and efficient route …

A three-component cascade reaction of 1, 3-enynes, anilines, and Togni-II reagent has been
developed to give fully substituted trifluoromethyl pyrroles with high regioselectivity under …

Pyrroles are important synthetic targets as a result of their occurrence in numerous
biologically active molecules, their important roles in diverse living processes, and their …