T cells in atherosclerosis

K Tse, H Tse, J Sidney, A Sette… - International immunology, 2013 - academic.oup.com
Atherosclerosis is a chronic inflammatory disease of the artery wall. Atherosclerotic lesions
contain monocytes, macrophages, smooth muscle cells and T lymphocytes. Here, we review …

Natural killer T cells: rapid responders controlling immunity and disease

JC Mercer, MJ Ragin, A August - The international journal of biochemistry & …, 2005 - Elsevier
Natural killer T (NKT) cells are a subset of T cells that share properties of natural killer cells
and conventional T cells. They are involved in immediate immune responses, tumor …

Distinct NKT cell subsets are induced by different Chlamydia species leading to differential adaptive immunity and host resistance to the infections

AG Joyee, H Qiu, S Wang, Y Fan, L Bilenki… - The Journal of …, 2007 - journals.aai.org
We investigated the role of NKT cells in immunity to Chlamydia pneumoniae and Chlamydia
muridarum infections using a combination of knockout mice and specific cellular activation …

CD1d‐restricted natural killer T cells are potent targets for human immunodeficiency virus infection

R Fleuridor, B Wilson, R Hou, A Landay… - …, 2003 - Wiley Online Library
Invariant human natural killer T cells (NKT) express a restricted T‐cell receptor (TCR)
Vα24Vβ11 repertoire. These cells share both phenotypic and functional similarities between …

NK T cell activation promotes Chlamydia trachomatis infection in vivo

L Bilenki, S Wang, J Yang, Y Fan… - The Journal of …, 2005 - journals.aai.org
We used two approaches to examine the role of NK T cells (NKT) in an intracellular bacterial
(Chlamydia trachomatis mouse pneumonitis (C. muridarum)) infection. One is to use CD1 …

Natural killer T cells contribute to airway eosinophilic inflammation induced by ragweed through enhanced IL‐4 and eotaxin production

L Bilenki, J Yang, Y Fan, S Wang… - European journal of …, 2004 - Wiley Online Library
Although NKT cells have been found to be capable of modulating immune responses in
several model systems, the role of NKT cells in allergy remains unclear. Using CD1 gene …

Expansion and hyperactivity of CD1d-restricted NKT cells during the progression of systemic lupus erythematosus in (New Zealand Black× New Zealand White) F1 …

C Forestier, A Molano, JS Im, Y Dutronc… - The Journal of …, 2005 - journals.aai.org
CD1d-restricted NKT cells expressing invariant TCR α-chain rearrangements (iNKT cells)
have been reported to be deficient in humans with a variety of autoimmune syndromes and …

CD4 T cells play major effector role and CD8 T cells initiating role in spontaneous autoimmune myocarditis of HLA-DQ8 transgenic IAb knockout nonobese diabetic …

SL Hayward, N Bautista-Lopez, K Suzuki… - The Journal of …, 2006 - journals.aai.org
In humans, spontaneous autoimmune attack against cardiomyocytes often leads to
idiopathic dilated cardiomyopathy (IDCM) and life-threatening heart failure. HLA-DQ8 …

Natural killer T cells are critical for dendritic cells to induce immunity in Chlamydial pneumonia

AG Joyee, H Qiu, Y Fan, S Wang… - American journal of …, 2008 - atsjournals.org
Rationale: We previously showed an important role of natural killer T cells (NKT) in skewing
the adaptive T cell immunity to Chlamydia pneumoniae (Cpn), an intracellular bacterial lung …

Natural killer T cells and atherosclerosis: form and function meet pathogenesis

NA Braun, R Covarrubias, AS Major - Journal of innate immunity, 2010 - karger.com
Atherosclerosis is a chronic inflammatory disease characterized by dyslipidemia and
accumulation of lipids in the arterial intima, with activation of both innate and adaptive …